Citrus is one of the most important fruit crops grown in the worldwide especially in Mediterranean countries. Deficit irrigation (DI) is a proposed strategy many years ago to overcome the scarcity of water especially in arid and semiarid regions. The vegetative growth, enzymatic activities, proline and phenolic content, fruit yield and quality in response to deficit irrigation levels (T1 (irrigation every 15 days as a control), T2 (irrigation every 20 days), T3 (irrigation every 25 days) and T4 (irrigation every 30 days), were evaluated. The results showed that the P, K, proline, phenols, vitamin C, SSC contents and catalase and peroxidase activities were increased by T2 and T3. While the N content, fruit yield, weight, peel thickness, juice volume, and transpiration rate were increased by T1 and T2 compared to T3 and T4. The fruit yield and weight, and physical properties were not negatively affected by light and medium deficit irrigation (T2 and T3), which was positively affected enzymatic activities, proline and phenols contents, and chemical fruit properties (SSC and Vitamin C).