The study aimed to evaluate the effectiveness of seven chemical nematicides in controlling second-stage juveniles of root-knot nematodes (Meloidogyne spp.) and lesion nematodes (Pratylenchus spp.) around the roots of date palm trees. The results revealed significant reductions in second-instar larvae in both types of nematodes compared to untreated palms, indicating the effectiveness of the tested nematicides in alleviating nematode infestation. One month after application, all treatments resulted in significant reductions in second-stage juveniles of root-knot nematode. The two compounds, Random and Velum Prime were the most effective among the nematicides tested, achieving reductions of 77.32% and 76.83%, respectively. Also, Mocap demonstrated significant efficacy, while the compounds Trans, Horinema, Canzafos, and Nimazone achieved moderate efficacy. In addition, after two months of treatment, Velum Prime maintained its strongest effectiveness, followed by Random and Mocap (97.96, 93.3 and 88.2% reduction, respectively). On the contrary, the results showed an increase in the number of nematodes in untreated palm trees, which confirms the importance of using chemical nematicides in combating nematodes. In contrast, for the evaluation of nematicides on the lesion nematode, Pratylenchus spp. The results showed that all of the tested nematicides achieved outstanding results after a month of treatment, except for the Trans compound, where its use resulted in a 34.73% reduction in population compared to the untreated palms, while all of the tested nematicides achieved a complete reduction after two months of addition of 100%, except Trans, which achieved 97.11% reduction in population compared to palms not treated with nematicides. These results confirm the important role played by chemical nematicides as one of the necessary treatments to reduce nematode infestation and draw attention to the importance of nematode control in date palm cultivation, which is considered one of the fruit trees that Egypt has been interested in in recent years.