Divalent Co, Ni, Cu, Zn and Cd chelates originating from methomyl (Lannate) were prepared, and their anti-molluscicidal activity was screened in vitro and in vivo against Eobania vermiculata using contact and spraying techniques, respectively. The results proved that each tested complex had varying degrees of sensitivity to the tested land snail species, with significant anti-molluscicidal activity. The laboratory test data demonstrated that CdCl₂ complex adopted the highest toxicity toward E. vermiculata species (LC₅₀ = 82.72 ppm). Eobania vermiculata was more susceptible to CoCl₂ complex (LC₅₀ = 100.09 ppm) than CuBr₂, CuCl₂, NiCl₂ and Cu(ClO₄)₂ complexes (LC₅₀ = 142.06, 147.61, 148.62  and 149.16 ppm, respectively). Whereas, ZnCl₂ complex exhibited the lowest toxicity among the screened coordinated constructions (LC₅₀ = 181.69 ppm). Field trials of tested compounds were applied by spraying technique and the population reduction percentage of Eobania vermiculata was evaluated. The field experiments showed that complexes (1, 3 and 4) achieved high population reduction percentages of E. vermiculata (94.22, 94.19 and 92.86%, respectively), while, complex (7) had the lowest toxic efficacy; it displayed only 3.27% reduction of Eobania vermiculata population.