Two field experiments were conducted at a private field in Qalin City, Kafr El sheikh Governorate, Egypt, during 2021/2022 and 2022/2023 seasons to study the response productivity and grain quality of some wheat cultivars (Sakha 95 and Misr-3) to seeding rates (30, 50 and 70 kg grains/fed) and nitrogen levels (50, 75 and 100 kg N/fed) under different sowing dates (25th Oct., 25th Nov. and 25th Dec.). Each sowing date was performed in separate experiment. Every experiment of sowing dates was carried out in split- split plot design with four replications. The main-plots were assigned to new Egyptian wheat cultivars. While, the sub-plots were randomly allocated to seeding rates. Whilst, the sub-sub plots were randomly distributed to nitrogen fertilizer levels. The obtained results revealed that the studied seasons, sowing dates, wheat cultivars, seeding rates and nitrogen fertilizer levels significantly affected No. of spikes/m2, spike length, No. of spikelets/spike, No. of grains/spike, 1000-grain weight, biological and grain yields/fed, harvest index (HI) and crude protein percentage in most cases. From the achieved results of this study, it could be recommended that sowing wheat Sakha 95 cultivar on 25th November with 50 kg grains/fed and fertilizing with 100 kg N/fed to obtain the highest productivity and grains quality under the environmental conditions of Qalin City, Kafrelsheikh Governorate, Egypt.