388310

Postpartum gangrene of three limbs complicating inotrope therapy: A case report

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Last updated: 05 Jan 2025

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Abstract

Background
Symmetrical peripheral gangrene (SPG) is an uncommon but devastating complication in critically ill patients with a high mortality. It is seldom seen in pregnancy and postpartum period.
Case presentation
We hereby report a 27-year-old woman diagnosed of having postpartum hemorrhagic shock. The patient developed symmetrical peripheral gangrene triggered possibly by sepsis and inotropes. The patient presented with consciousness disturbance and hemodynamically unstable condition. Owing to the unstable hemodynamic status, inotropic agents with maximum dose of dopamine at 17 mcg/kg/min and norepinephrine of 8 mcg/kg/min were used. On the 4th day of admission, the patient developed gangrene and compartmental syndrome in the limbs. However, even with the dose of inotropic agents tapered, the gangrene did not resolve. So, multiple amputations and fasciotomy were done. Patient also developed acute kidney injury with anuria, thus necessitating hemodialysis treatment.
Conclusion
Although postpartum hemorrhagic shock is of high risk for sepsis and use of inotropes is common, occurrence of peripheral gangrene is rare. A high index of suspicion for the diagnosis and timely intervention will prevent irreparable damage and loss of limb.

DOI

10.1016/j.egja.2014.03.011

Authors

First Name

Ahmed S.

Last Name

El-agwany

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First Name

Ziad S.

Last Name

Abouzaid

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First Name

Nashwa A.

Last Name

Mekhemar

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Volume

30

Article Issue

4

Related Issue

51187

Issue Date

2014-10-01

Receive Date

2013-08-18

Publish Date

2014-10-01

Page Start

435

Page End

437

Print ISSN

1110-1849

Online ISSN

1687-1804

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https://egja.journals.ekb.eg/article_388310.html

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https://egja.journals.ekb.eg/service?article_code=388310

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388,310

Publication Type

Journal

Publication Title

Egyptian Journal of Anaesthesia

Publication Link

https://egja.journals.ekb.eg/

MainTitle

Postpartum gangrene of three limbs complicating inotrope therapy: A case report

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Article

Created At

21 Dec 2024