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388012

The effect of dexamethasone as an adjuvant in quadratus lumborum block to improves analgesia after laparoscopic cholecystectomy: Controlled randomized study

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Last updated: 29 Dec 2024

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Abstract

Background
The pain following a laparoscopic cholecystectomy is multifaceted; Therefore, it can be controlled by multimodal methods such as Transmuscular Quadratus Lumborum Block (TQLB) and analgesics.
Objectives
Determine the effectiveness of TQLB using Bupivacaine or Bupivacaine-Dexamethasone in improving the quality of analgesia after laparoscopic cholecystectomy procedures.
Methods
Under general anesthesia, ninety patients, ranging in age from eighteen to sixty, were scheduled for elective laparoscopic cholecystectomy surgery. Three groups of patients (30 patients in each) were randomly assigned who underwent bilateral ultrasound guided TQLB injected with 21 ml of the drug on each side. The Bupivacaine group (B) received (20 ml Bupivacaine hydrochloride 0.25% + 1 mL 0.9% normal saline); the Dexamethasone-Bupivacaine group (D) received (20 ml Bupivacaine hydrochloride 0.25% + 1 mL dexamethasone 4 mg); and the Control group (C) received (21 ml 0.9% normal saline).
Results
The initial analgesic request was significant longer in group D (18 h) more than B (14 h), and C (0.8 h). The total analgesic requirements were increased in group C. The visual Analogue Score at rest and movement always revealed no significant distinctions between groups B and D. However, all values were raised in the control group more than in the other groups. The percentage of patients who were satisfied with the technique was greater in groups B and D than in group C.
Conclusions
Ultrasound guided TQLB is a useful technique for raising patient satisfaction and analgesic quality. Furthermore, the addition of dexamethasone can prolong the duration of analgesia and decrease the postoperative Analgesia requirement.

DOI

TEJA-2023-0240

Keywords

dexamethasone, Quadratus Lumborum block, Laparoscopic cholecystectomy

Authors

First Name

Haidy Salah

Last Name

Mansour

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Affiliation

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Orcid

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First Name

Nagy Sayed

Last Name

Ali

MiddleName

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Affiliation

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Email

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Orcid

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First Name

Mohamed Adel

Last Name

Abdel Rahman

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Volume

40

Article Issue

1

Related Issue

51165

Issue Date

2024-12-01

Receive Date

2023-09-30

Publish Date

2024-12-31

Page Start

135

Page End

142

Print ISSN

1110-1849

Online ISSN

1687-1804

Link

https://egja.journals.ekb.eg/article_388012.html

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https://egja.journals.ekb.eg/service?article_code=388012

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388,012

Publication Type

Journal

Publication Title

Egyptian Journal of Anaesthesia

Publication Link

https://egja.journals.ekb.eg/

MainTitle

The effect of dexamethasone as an adjuvant in quadratus lumborum block to improves analgesia after laparoscopic cholecystectomy: Controlled randomized study

Details

Type

Article

Created At

21 Dec 2024