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387992

Effect of addition of different additives: Magnesium sulfate and dexamethasone versus plain bupivacaine in ultrasound-guided erector spinae plane block in pediatrics undergoing r

Article

Last updated: 29 Dec 2024

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Abstract

Background
Erector spinae plane (ESP) block has been evaluated in many studies in pediatric surgeries by the use of postoperative rescue analgesia which is the objective parameter assessing the efficacy of the technique in controlling postoperative pain. Adjuvants were used with ESP block to densify its postoperative analgesia. Magnesium sulfate was used for suppressing somatic, endocrine and autonomic reflexes induced by noxious stimuli during surgery. Dexamethasone is a highly potent glucocorticoid that has been used in different regional anesthesia to prolong the anesthetic effect of the local anesthesia by inducing local vasoconstriction.
Methodology
Sixty pediatric patients underwent inguinal hernia repair under general anesthesia, and then they were assigned randomly into three groups that received ESP block either with local anesthetic alone or with magnesium sulfate or dexamethasone.
Results
Our study revealed no statistical significance among the three groups as regards demographic and vital data. Children’s Hospital Eastern Ontario Pain Scale score for postoperative assessment of magnesium sulfate and dexamethasone which were added to bupivacaine in ESP block had a better score than bupivacaine alone with high statistical significance. Also, magnesium sulfate and dexamethasone had a delayed first-dose postoperative rescue analgesia with significant statistical value ( value = 0.002) and total postoperative doses of postoperative rescue analgesia were lesser in magnesium sulfate and dexamethasone groups with marked statistical significance ( value < 0.001). As regards complications, there were minor ones in the form of mild bruising and mild pain at injection site with no statistical significance between the three groups ( value = 0.108).
Conclusion
In our study, magnesium sulfate and dexamethasone added to bupivacaine in ESP block prolonged the duration of postoperative pain control and decreased the consumption of postoperative analgesia than bupivacaine alone. No major complications were recorded in our study in the three groups which solidify the safety of the technique.

DOI

TEJA-2023-0229

Keywords

Erector spinae plane block, Inguinal hernia repair, magnesium sulfate, dexamethasone

Authors

First Name

Fatma

Last Name

Ahmed Mostafa Aref

MiddleName

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City

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Orcid

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First Name

Nabila Mohammed

Last Name

Abdelaziz

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Hesham Mohammed

Last Name

Elazazzi

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Niven Gerges

Last Name

Fahmy

MiddleName

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Affiliation

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Email

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City

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Orcid

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Volume

39

Article Issue

1

Related Issue

51163

Issue Date

2023-12-01

Receive Date

2023-09-01

Publish Date

2023-12-31

Page Start

906

Page End

911

Print ISSN

1110-1849

Online ISSN

1687-1804

Link

https://egja.journals.ekb.eg/article_387992.html

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https://egja.journals.ekb.eg/service?article_code=387992

Order

387,992

Publication Type

Journal

Publication Title

Egyptian Journal of Anaesthesia

Publication Link

https://egja.journals.ekb.eg/

MainTitle

Effect of addition of different additives: Magnesium sulfate and dexamethasone versus plain bupivacaine in ultrasound-guided erector spinae plane block in pediatrics undergoing repair of inguinal hernia

Details

Type

Article

Created At

21 Dec 2024