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387768

Efficacy of adding dexmedetomidine as adjuvant with bupivacaine in ultrasound-guided erector spinae plane block for post thoracotomy pain: Randomized controlled study

Article

Last updated: 31 Dec 2024

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Abstract

Background
Poor management of postoperative pain results in physiological and psychological side effects with higher morbidity. Erector spinae plane block (ESPB) has shown efficacy in controlling pain in many surgeries. Dexmedetomidine has improved the quality of analgesia in many regional techniques. This study aimed to assess the analgesic outcome of adding dexmedetomidine to bupivacaine in ultrasound (US) guided ESPB for perioperative analgesia for thoracic cancer surgeries.
Patients and Methods
In this randomized controlled, double-blind study, 42 patients aged 18–65 years, ASA (American Society of Anesthesiologists) physical status II, scheduled for thoracotomy for cancer surgeries under general anesthesia were included. Patients were allocated into two equal groups: group 1 (ESPB by 28 ml bupivacaine 0.25% + 2 mL saline) and group 2 (ESPB 28 ml bupivacaine 0.25% + 2 mL dexmedetomidine 0.5 µg/kg). Blocks were performed before anesthesia induction.
Results
Group 2 consumed lower intraoperative fentanyl and postoperative morphine and had a lower pain score at rest and cough compared to group 1. Group 2 had prolonged time to first request of rescue analgesia compared to group 1. Postoperative nausea and vomiting, and sedation were comparable between both groups. No block-related complications were observed.
Conclusions
Adding dexmedetomidine to bupivacaine in US-guided ESPB provided more effective and safe analgesia in thoracotomy.

DOI

TEJA-2021-0106

Keywords

Erector spinae plane block, Dexmedetomidine, thoracotomy, Postoperative Analgesia

Authors

First Name

Mamdouh Mahmoud

Last Name

Elshal

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Reham Mohamed

Last Name

Gamal

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Aya Mohamed

Last Name

Ahmed

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Nevine Mahmoud

Last Name

Gouda

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Mohamed Mohammed

Last Name

Abdelhaq

MiddleName

-

Affiliation

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Email

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City

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Orcid

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Volume

37

Article Issue

1

Related Issue

51159

Issue Date

2021-01-01

Receive Date

2021-07-22

Publish Date

2021-01-01

Page Start

425

Page End

431

Print ISSN

1110-1849

Online ISSN

1687-1804

Link

https://egja.journals.ekb.eg/article_387768.html

Detail API

https://egja.journals.ekb.eg/service?article_code=387768

Order

387,768

Publication Type

Journal

Publication Title

Egyptian Journal of Anaesthesia

Publication Link

https://egja.journals.ekb.eg/

MainTitle

Efficacy of adding dexmedetomidine as adjuvant with bupivacaine in ultrasound-guided erector spinae plane block for post thoracotomy pain: Randomized controlled study

Details

Type

Article

Created At

21 Dec 2024