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Evaluation of unilateral ultrasound guided paravertebral block for perioperative analgesia in cancer patients undergoing lower limb sparing surgeries: A prospective randomized co

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Last updated: 05 Jan 2025

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Abstract

Background
Formerly management of malignant tumors of lower limb was mainly through amputation. After advancement in neoadjuvant chemo-radiotherapy, saving the limb through lower limb-sparing surgery became the main line for management. Different regional techniques are used for perioperative pain control in limb-sparing surgeries. One of these techniques is lumbar paravertebral block. It is a regional technique that provides ipsilateral analgesia resulting in somatic and sympathetic blockade in a continuous dermatomal manner.
Methods
The study included 60 cancer patients scheduled for lower limb sparing surgeries. Patients were randomly allocated into two groups to receive either lumbar paravertebral block Group P with 25 ml of Bupivacaine 0.25%, with adrenaline 1:200,000 or general anesthesia Group C.
Results
There was a statistically significant decrease in hemodynamics values for Group P compared to Group C at most of the study times. Intraoperative fentanyl consumption was lower in Group P compared to Group C (107.1 ± 22.89 ug versus 233.43 ± 49.29 ug), respectively. VAS scores were lower for Group P compared to Group C with lower postoperative morphine consumption in Group P compared to Group C (8.65 ± 3.57 mg versus 16 ± 3.15 mg) respectively.
Conclusion
Ultrasound guided paravertebral block can be used as an effective perioperative analgesic modality for cancer patients undergoing lower limb sparing surgeries.

DOI

TEJA-2021-0105

Keywords

paravertebral block, Analgesia, Cancer, lower limb surgeries

Authors

First Name

Yasmen F.

Last Name

Mohamed

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Orcid

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First Name

Sayed M.

Last Name

Abed

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Affiliation

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Email

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Orcid

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First Name

Tamer M.

Last Name

Khair

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Ahmed

Last Name

Abdalla Mohamed

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Enas

Last Name

Samir

MiddleName

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Affiliation

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Email

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Orcid

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First Name

Walaa Y.

Last Name

Elsabeeny

MiddleName

-

Affiliation

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City

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Orcid

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Volume

37

Article Issue

1

Related Issue

51159

Issue Date

2021-01-01

Receive Date

2021-07-21

Publish Date

2021-01-01

Page Start

402

Page End

409

Print ISSN

1110-1849

Online ISSN

1687-1804

Link

https://egja.journals.ekb.eg/article_387765.html

Detail API

https://egja.journals.ekb.eg/service?article_code=387765

Order

387,765

Publication Type

Journal

Publication Title

Egyptian Journal of Anaesthesia

Publication Link

https://egja.journals.ekb.eg/

MainTitle

Evaluation of unilateral ultrasound guided paravertebral block for perioperative analgesia in cancer patients undergoing lower limb sparing surgeries: A prospective randomized co

Details

Type

Article

Created At

21 Dec 2024