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359918

Clinical profile and investigations of acute kidney injury in neonates admitted to NICU.

Article

Last updated: 05 Jan 2025

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Tags

Clinical Biochemistry

Abstract

 Background: Recent studies showed that critically ill neonates who were admitted to the neonate intensive care unit (NICU) may develop acute kidney injury (AKI) due to several risk factors thus resulting in a high mortality rate.
Purpose: Diagnosis of acute kidney injury in neonates admitted to Neonatal Intensive Care Units.
Patients and Methods: This was a case-control study. Conducted at the NICU, Faculty of Medicine Beni-Suef University Hospital from August 2020 to March 2021. The current study was conducted on 55 neonates (35 critically ill neonates and 20 healthy neonates admitted for phototherapy as a control group)
Results: The gestational age didn't show significant differences between cases and controls. Body weight showed a significant decrease in neonates with sepsis in comparison with controls. The respiratory rate (RR) and systolic blood pressure (BP) were significantly elevated in cases compared to the control. Hemoglobin and platelets were significantly lower in cases than controls while white blood cells were significantly increased in cases compared to controls. Plasma creatinine level was significantly elevated in cases compared to controls
Conclusion: 30% of neonates admitted to NICU developed AKI, especially with risk factors such as high RR, high systolic BP, anemia, and thrombocytopenia 

DOI

10.21608/ijabmb.2024.359918

Keywords

Neonatal AKI, NICU

Authors

First Name

Heba Mustafa

Last Name

Ahmed

MiddleName

-

Affiliation

Department of pediatrics, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Email

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City

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Orcid

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First Name

Noha A.

Last Name

Doudar

MiddleName

-

Affiliation

Department of Clinical and chemical Pathology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Email

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City

-

Orcid

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First Name

Sara Hosny

Last Name

Ahmed

MiddleName

-

Affiliation

Department of pediatrics, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Email

-

City

-

Orcid

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First Name

Osama Ezzat

Last Name

Botrous

MiddleName

-

Affiliation

Department of pediatrics, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.

Email

-

City

-

Orcid

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Volume

1

Article Issue

1

Related Issue

48441

Issue Date

2024-01-01

Receive Date

2024-06-10

Publish Date

2024-01-01

Page Start

33

Page End

40

Print ISSN

3009-7630

Online ISSN

3009-7991

Article File

IJABMB_Volume 1_Issue 1_Pages 33-40.pdf

PDF . 304.6kB

Link

https://ijabmb.journals.ekb.eg/article_359918.html

Detail API

https://ijabmb.journals.ekb.eg/service?article_code=359918

Order

359,918

Type

Original Article

Type Code

3,170

Publication Type

Journal

Publication Title

International Journal of Applied Biochemistry and Molecular Biology

Publication Link

https://ijabmb.journals.ekb.eg/

MainTitle

Clinical profile and investigations of acute kidney injury in neonates admitted to NICU.

Details

Type

Article

Created At

21 Dec 2024