Background:  A resilience perspective promotes a new way of seeing, by arguing that organizations are more effective than threat rigidity and what other deterministic perspectives allow. Although leadership has always been more difficult in challenging times, the unique stressors that organizations are facing worldwide today call for a renewed focus on what constitutes genuine leadership, and the need for authentic leadership has become obvious. Strengthening resilience helps nurses to engage in positive organizational citizenship behavior and an individual's ability to successfully cope with stress. Aim: the current study aimed to assess relationship between resilience and organizational citizenship behaviour among staff nurses. Design: A descriptive correlational design was used to carry out this study. Setting: This study was conducted at Ain-shams University Hospital which affiliated to Ain-shams University Hospital include two buildings: The first building consists of three floors are limited to administrative offices and the bone marrow transplant unit, the second building consists of five floors and contain all units and departments in the hospital (37) units and departments It's composed of 20 departments and 13 intermediate and intensive care units and 4 outpatient clinic. It provides care for patients in different medical specialties with a wide range of ambulatory care services such as outpatient, pharmacy, emergency, x-ray, physiotherapy, and paramedical services as dietary, laundry and maintenance. The total capacity is 601 beds. Tools of Data collection: the current study was collected by two tools namely; Resilience scale and Organizational citizenship behavior scale. Results: More than three fifths (61%) of staff nurses had a high level of resilience. While less than one fifth (18%) of them had low level of resilience. More than half (53.5%) of staff nurses had a high level of organizational citizenship behavior. While more than one fifth (22%) of them had low level of organizational citizenship behavior. Conclusion: There was a highly positive correlation between resilience and organizational citizenship behavior among staff nurses. Recommendations: Designing and creating an organizational environment that nurtures resilience could be an effective way of making people resilient and committed.