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383939

Evaluation of linear scars revision with and without platelet-rich fibrin and autologous unprocessed bone marrow injection

Article

Last updated: 05 Jan 2025

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Abstract

Introduction: There are many modalities of traditional methods of linear scar treatment including derma abrasion,
chemical ablation, laser therapy, and use of surgical excision and grafting. However, surgical treatments, with or without
supplementary nonsurgical treatments offers a confusing picture of widely variable ‘success' rates, recurrence rates,
patient populations, and follow-up periods.
Aim: Our main objective was to improve the results of treatment of linear scars. Also to evaluate of the results of adding
platelet-rich fibrin (PRF) and autologous unprocessed bone marrow in surgically revised linear scars.
Patients and Methods: Total study number of 16 patients (nine men, seven women), aged 22–52 years were enrolled in
this study. Six patients had the scar in the abdomen, four patients had the scar in the forearm, three in the leg and three
in the neck. Assessment of scar was done including history, clinical examination using Vancouver Scar Scale, patient'
and doctor' scar satisfaction. All patients were treated with scar revision by injecting half of the wound with the aspirated
autologous unprocessed bone marrow and PRF. On follow-up, the patients were photographed at the start of the study
(preoperative), weekly for first 2 weeks (postoperative), and monthly for the next 6 months.
Results: Adding heparinized autologous unprocessed bone marrow and PRF; may improve the pattern of scar revision.
This preliminary work suggests that there were differences in the time of healing, scar appearance (100%) as P value was
0.021, pliability, height (62.5%) a P value was (0.009), vascularity and satisfaction (43.8%) between both groups of the
study.
Conclusion: This novel treatment appeared to be safe and effective for scar treatment. To illustrate significant statistical
differences, we need a larger sampling and longer follow-up periods.

DOI

10.21608/EJSUR.2024.279882.1036

Keywords

Bone marrow, Mesenchymal Stem Cells, Platelet rich fibrin, scars revision, Wound healing

Authors

First Name

Abdel

Last Name

Basha

MiddleName

R.

Affiliation

Department of Surgery, Suez Canal University Hospitals, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

-

City

-

Orcid

-

First Name

Ashraf

Last Name

Hussein

MiddleName

-

Affiliation

Department of Surgery, Suez Canal University Hospitals, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

dr_ashrafhussein@yahoo.com

City

-

Orcid

-

First Name

Osama

Last Name

Antar

MiddleName

-

Affiliation

Department of Surgery, Suez Canal University Hospitals, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

osamaantaradly@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Elyamany

MiddleName

-

Affiliation

Department of Surgery, Suez Canal University Hospitals, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Email

yamany1110@yahoo.com

City

-

Orcid

-

Volume

43

Article Issue

4

Related Issue

50769

Issue Date

2024-10-01

Receive Date

2024-10-04

Publish Date

2024-10-01

Page Start

1,202

Page End

1,209

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_383939.html

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https://ejsur.journals.ekb.eg/service?article_code=383939

Order

383,939

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

Evaluation of linear scars revision with and without platelet-rich fibrin and autologous unprocessed bone marrow injection

Details

Type

Article

Created At

21 Dec 2024