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376374

RESULTS OF MANAGEMENT OF COLORECTAL CARCINOMA

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Last updated: 21 Dec 2024

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Abstract

Background: Colorectal cancer is the only commonly curable visceral malignancy constituting a significant problem as 
its outcome has remained poor and nearly unchanged over the last 25 years. This study has been performed to outline results of management of colorectal carcinoma. 
Patients and Methods: 78 patients with colorectal carcinoma included in this study with Dukes'A, B and C stages. 
Investigations, surgical treatment and histopathological studies were carried out. Adjuvant treatment was adopted in 
selected cases. Carcinoembryonic antigen estimation was performed. Follow-up in only 73 patients was carried out, who 
passed the postoperative period (4 weeks). Patterns of relapse and overall survival were outlined in follow-up cases for 42 months. 
Results: Relapse was encountered in 45.2% of patients. Most patients with Dukes'C had relapse (79.3%) and to less 
extent those with Dukes'B (23.5%). 42.9% of rectal carcinoma showed local relapse and 25% of colonic carcinoma showed local relapse. 87.5% of patients with mucinous carcinoma showed relapse and only 33.3% of non-mucinous carcinoma 
showed relapse. Overall survival was 51% at 42 months according to the Kaplan-Meier method. Patients with Dukes'A had the best survival rate (80%), followed by Dukes'B (64%) and Dukes'C (27%). Dukes' stages, type of pathology and relapse of tumor had a statistically significant difference on overall survival. 
Conclusion: This study outlined results of management of colorectal carcinoma and guidelines of surgical and adjuvant 
treatment. 

DOI

10.21608/ejsur.2001.376374

Keywords

Colorectal carcinoma, anterior resection, abdominoperineal resection, CEA

Authors

First Name

Mansour

Last Name

M. Kabash

MiddleName

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Affiliation

Surgery, South Valley University

Email

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City

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Orcid

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First Name

Ali

Last Name

Abd El-Rahman Abd-Alla

MiddleName

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Affiliation

Radiotherapy and Microbiology, South Valley University

Email

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City

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Orcid

-

First Name

Ahmed

Last Name

Hassan

MiddleName

-

Affiliation

Immunology Departments, South Valley University

Email

ahmed.hassan.eltarasha@med.asu.edu.eg

City

-

Orcid

-

First Name

Abdel-Hadi

Last Name

Omar

MiddleName

-

Affiliation

Pathology Department, Assiut Faculty of Medicine. Egypt.

Email

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City

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Orcid

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Volume

20

Article Issue

2

Related Issue

50042

Issue Date

2001-04-01

Receive Date

2024-08-27

Publish Date

2001-04-01

Page Start

529

Page End

540

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_376374.html

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https://ejsur.journals.ekb.eg/service?article_code=376374

Order

376,374

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

RESULTS OF MANAGEMENT OF COLORECTAL CARCINOMA

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Article

Created At

21 Dec 2024