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374676

STENTED AUTOLOGUS VEIN GRAFT VERSUS GORE-TEX TUBE GRAFT FOR THE REPAIR OF COMMON BILE DUCT DEFECTS AN EXPERIMENTAL STUDY

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Last updated: 05 Jan 2025

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Abstract

This experimental study compared the effectiveness of using a stented autologus vein graft versus Gore-Tex tube graft in 
the repair of large defects of the common bile duct (CBD) in a canine model. A 3-cm segment of the great saphenous vein and a 2-cm segment of the CBD were removed from ten healthy dogs with normal blood biochemistry levels (Group A). A stent was introduced into the proximal end of the CBD, through the vein segment and into the distal end of the CBD. The venous graft was then sutured to the CBD. A 2-cm segment of the CBD was removed and was replaced with a 2-cm segment of Gore-Tex tube for another ten healthy dogs with normal blood biochemistry levels (Group B). A liver biopsy was taken for histopathological examination during laparotomy and relaparotomy 15 days after graft implantation. Blood samples were obtained for biochemical examinations on postoperative days 5,10 and 15. In Group A, 1 dog died after 5 days with complete disruption in the upper anastomosis and biliary leakage (10%). Complete healing of the anastomosis occurred in 9 dogs (90%). In Group B 3 dogs (30%) died with complete disruption in the upper anastomosis (2 dogs- 20%) and in both anastomoses (1 dog -10%) and biliary leakage. Partial disruption occurred in the upper anastomosis in 3 dogs (30%) and in the lower anastomosis in 2 dogs (20%) with biliary leakage. Complete healing was confirmed in 2 dogs (20%). In the 7 surviving dogs the Gore–Tex graft was surrounded by fibrosis and its lumen was obturated by clots in 2 dogs (20%). No changes in liver biopsies or blood biochemistry were observed in surviving dogs of either group. 
We conclude that the use of an autologus vein graft and stent to repair CBD injuries could be a feasible method of treatment and that its use is more effective, safe, economic and practical than Gore-Tex tube graft although it is more difficult and time consuming. We found that the Gore-Tex tube graft is not a god alternative to repair CBD injuries but longer follow up may yield a better outcome.

DOI

10.21608/ejsur.2003.374676

Keywords

Repair of common bile duct defects, Stented autologus vein graft, Gore, Tex graft

Authors

First Name

Ibrahim

Last Name

H. Othman

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Affiliation

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt

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First Name

Abdel-Moneim

Last Name

A. Nagy

MiddleName

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Affiliation

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt

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Orcid

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First Name

Ayman

Last Name

A. El Nemr

MiddleName

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Affiliation

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt

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First Name

Mohammad

Last Name

H. El Henedy

MiddleName

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Affiliation

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt

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Orcid

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First Name

Sherief

Last Name

A. Mostafa

MiddleName

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Affiliation

Department of General Surgery, Faculty of Medicine, Tanta University, Egypt

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Orcid

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First Name

Fersan

Last Name

A. Sallam

MiddleName

-

Affiliation

Department of Pathology,Faculty of Medicine, Tanta University, Egypt

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Volume

22

Article Issue

2

Related Issue

49846

Issue Date

2003-04-01

Receive Date

2024-08-18

Publish Date

2003-04-01

Page Start

145

Page End

149

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_374676.html

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https://ejsur.journals.ekb.eg/service?article_code=374676

Order

374,676

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

STENTED AUTOLOGUS VEIN GRAFT VERSUS GORE-TEX TUBE GRAFT FOR THE REPAIR OF COMMON BILE DUCT DEFECTS AN EXPERIMENTAL STUDY

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Article

Created At

21 Dec 2024