Aim: This study addressed a modified microcoeliotomy approach, through the subxiphoid minimal stress triangle, for 
cholecystectomy in gallstone disease. 
Methods: From February 2001 to 2004, at Tanta University Hospital, 50 patients with chronic calcular cholecystitis were 
prospectively randomized into two equal groups: Group I: 25 patients for whom the modified microcoeliotomy 
cholecystectomy technique had been done. Group II: 25 patients for whom the laparoscopic approach had been done. Their ages ranged from 22 to 65 years (mean ± SD = 40 ± 11.7) with 38 females and 12 males (3.17: 1). The whole follow-up period ranged from 3-24 months with a mean of 14 months. 
Results: In group I and II respectively, the operative time was 75 ±10.9 and 45 ±4.6 minutes, intraoperative bleeding occurred in 0% and 4%, hospital stay was 2.13 ±0.3 and 2.17 ±0.37 days, postoperative pain score was 4 ±0.87 and 5 ±1.12, vomiting occurred in 41.7% and 62.5% of patients, off-work time was 6.3 ±1.08 and 6.6 ±1.98 days and no early or late postoperative jaundice.. 
Conclusion: Subxiphoid minimal stress triangle modified microcoeliotomy cholecystectomy technique is a viable, safe, 
feasible and cheaper alternative to the laparoscopic cholecystectomy.