Beta
373736

CONTROVERSIES IN THE SURGICAL THERAPY OF DIFFERENTIATED THYROID CARCINOMA: A REPLICATION STUDY REVIEWING 32 CASES

Article

Last updated: 29 Dec 2024

Subjects

-

Tags

-

Abstract

Objective: reevaluation of experience with total versus near total thyroidectomy(TT)in treatment of differentiated thyroid 
carcinoma. 
Design: 32 cases of differentiated thyroid carcinoma(21 papillary and 11 follicular) were allocated to receive either total 
thyroidectomy TT or near total thyroidectomy(NTT)from 1994 through 1997. In TT group, thyroid bed biopsies were taken intraoperatively and the postoperative RAI131 study was assessed to evaluate thoroghness of TT, also extensive 
histopathologc examination of the contralateral lobe was done to detect multicentric foci. Patients were followed up 
clinically, biochemically and radiologically to detect complications and recurrences. 
Results: In TT group, 15of16 cases(93.8%)showed residual uptake in the neck. Also thyroid bed biopsies revealed thyroid 
tissue in 12(75%), and contralateral lobe revealed cancerous foci in 6(37.5%). 4 of TT group(25%)developed permanent 
hypoparathyroidism and one developed permanent RLN palsy. 
In NTT group one developed transient hypoparathyroidism and one developed RLN palsy. 7 cases(20.8%)developed 
recurrences, 3 in TT group and 4 in NTT group. And 5(15.6%)have died during follow up period, 2 in TT group and 3 in NTT group, all were follicular carcinomas. All cases with papillary carcinoma are still alive. 
Conclusion: TT Vs NTT appear to bear no significant difference regarding recurrences and overall survival, despite an 
increased rate of complications in case of TT. 

DOI

10.21608/ejsur.2004.373736

Keywords

Total Thyroidectomy, near total thyroidectomy, radioactive iodine, Recurrent laryngeal nerve

Authors

First Name

Alaa

Last Name

M. El-Erian

MiddleName

-

Affiliation

Department of surgery, teaching institutes & hospitals

Email

-

City

-

Orcid

-

First Name

Reda

Last Name

Saad

MiddleName

-

Affiliation

Department of surgery, Ain shams University

Email

redaez@hotmail.com

City

-

Orcid

-

First Name

Maher

Last Name

Fathy

MiddleName

-

Affiliation

Department of surgery, teaching institutes & hospitals

Email

-

City

-

Orcid

-

Volume

23

Article Issue

4

Related Issue

49800

Issue Date

2004-10-01

Receive Date

2024-08-14

Publish Date

2004-10-01

Page Start

359

Page End

365

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_373736.html

Detail API

https://ejsur.journals.ekb.eg/service?article_code=373736

Order

373,736

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

CONTROVERSIES IN THE SURGICAL THERAPY OF DIFFERENTIATED THYROID CARCINOMA: A REPLICATION STUDY REVIEWING 32 CASES

Details

Type

Article

Created At

21 Dec 2024