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373068

IMPROVED 5-YEAR DISEASE FREE SURVIVAL BY EXTENDED CLEARANCE OF THE PELVIS DURING RADICAL CYSTECTOMY FOR LOCALLY ADVANCED BILHARIZAL BLADDER CANCER "STAGE P3 AND P4a"

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Last updated: 29 Dec 2024

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Abstract

Aim: To reduce the possibility of local pelvic recurrence after radical cystectomy for stage P3 and P4a bilharzial bladder 
cancer by performing extended pelvic dissection in order to accomplish complete clearance of the anterior part of the pelvic cavity. 
Methods: A prospective study which was done in the period between 1998 and 2000. Forty-one patients (38 males and 3 females) having stage P3 – P4a bilharzial bladder cancer underwent radical cystectomy (or anterior pelvic excentration in 
females) with extended pelvic dissection to include and remove the parietal endopelvic fascia to achieve complete clearance of the anterior part of the pelvic cavity. Five patients were excluded and 36 patients were followed up for 5 years. 
Results: There was one post-operative mortality. Local recurrence occurred in 16.6% of these patients. Five patients with 
tumor invasion to the prostate developed early vertebral metastases. The 5 year Disease Free Survival for all patients in 
stage P3 and P4a was 55.6%. It was 67.9% for stage P3 patients and was only 12.5% for stage P4a patients. 
Conclusion: A reduced incidence of pelvic recurrence could be achieved by a meticulaous and extended pelvic dissection to achieve complete clearance of the anterior part of the pelvic cavity. 
Tumor invasion to the prostate represents a major problem that could be studied and solved. 

DOI

10.21608/ejsur.2006.373068

Keywords

Urinary tract neoplasms, Schistosomiasis, Surgery

Authors

First Name

Amr

Last Name

Selim

MiddleName

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Affiliation

Department of Surgery, National Cancer Institute, Cairo University, Egypt

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Orcid

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First Name

Akram

Last Name

Nouh

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Affiliation

Department of Pathology, National Cancer Institute, Cairo University, Egypt

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Volume

25

Article Issue

3

Related Issue

49752

Issue Date

2006-07-01

Receive Date

2024-08-10

Publish Date

2006-07-01

Page Start

163

Page End

168

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_373068.html

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https://ejsur.journals.ekb.eg/service?article_code=373068

Order

373,068

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

IMPROVED 5-YEAR DISEASE FREE SURVIVAL BY EXTENDED CLEARANCE OF THE PELVIS DURING RADICAL CYSTECTOMY FOR LOCALLY ADVANCED BILHARIZAL BLADDER CANCER "STAGE P3 AND P4a"

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Article

Created At

21 Dec 2024