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372309

ROLE OF RADIOFREQUENCY ABLATION IN THE TREATMENT OF COLORECTAL LIVER METASTASES

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Last updated: 29 Dec 2024

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Abstract

Aim: Surgical resection is the standard of care for colorectal metastases isolated to the liver. However, only 10–25% are 
eligible for resection because of extent and location of the disease in the liver or concurrent medical conditions. Several series have shown that radiofrequency ablation (RFA) can result in tumor eradication in properly selected candidates.The purpose of this study was to determine the efficacy of RFA for treatment of such lesions 
Methods: Thirty patients with documented colorectal liver metastases who met the following criteria were considered for 
RFA: metastases confined to the liver; judged irresectable due to technical considerations or co-morbidity, number of 
metastatic deposits no greater than 5; and size less than 10 cm. 
Results: Median follow-up was 26 (range 9-63) months. Overall 1-and 2-year survival rates were 76 and 61% respectively. 
Median survival was 32 months. Disease-free survival at 1 year was 35% at 2 years 7%. Six patients developed recurrence at the site of RFA; given that the total number of RFA-treated lesions was 69 the local recurrence rate was 9%. 
Conclusion: RFA can achieve effective local treatment for patients with colorectal liver metastases who were considered 
unsuitable for surgical treatment. 

DOI

10.21608/ejsur.2007.372309

Keywords

Local-ablative therapy, Irresectable Tumor, Hepatic Secondaries

Authors

First Name

Hesham

Last Name

Abdeldayem

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Ibrahim

Last Name

Abdelkader

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Maher

Last Name

Osman

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Hesham

Last Name

Gad

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Essam

Last Name

Salah

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Amr

Last Name

Helmy

MiddleName

-

Affiliation

Department of Surgery, National Liver Institute, Menoufeyia University

Email

-

City

-

Orcid

-

First Name

Tarek

Last Name

Essam El-deen

MiddleName

-

Affiliation

National Cancer Institute, Cairo University

Email

-

City

-

Orcid

-

First Name

Ahmad

Last Name

Touny

MiddleName

-

Affiliation

National Cancer Institute, Cairo University

Email

-

City

-

Orcid

-

First Name

Ossama

Last Name

Elabd

MiddleName

-

Affiliation

Radiology National Liver Institute, Menoufeyia University, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed

Last Name

El-Waraky

MiddleName

-

Affiliation

Radiology National Liver Institute, Menoufeyia University, Egypt

Email

-

City

-

Orcid

-

Volume

26

Article Issue

3

Related Issue

49668

Issue Date

2007-07-01

Receive Date

2024-08-07

Publish Date

2007-07-01

Page Start

115

Page End

119

Print ISSN

1110-1121

Online ISSN

1687-7624

Article File

EJSUR_Volume 26_Issue 3_Pages 115-119.pdf

PDF . 614.3kB

Link

https://ejsur.journals.ekb.eg/article_372309.html

Detail API

https://ejsur.journals.ekb.eg/service?article_code=372309

Order

372,309

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

ROLE OF RADIOFREQUENCY ABLATION IN THE TREATMENT OF COLORECTAL LIVER METASTASES

Details

Type

Article

Created At

21 Dec 2024