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367346

POST-THYROIDECTOMY HYPOCALCAEMIA: CLINICAL AND HISTOPATHOLOGICAL STUDY

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Last updated: 21 Dec 2024

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Abstract

Aim: To study the relation between post- thyroidectomy clinical hypocalcaemia and histopathological 
finding of parathyroid tissue. 
Methods: From Jan 2006 to June 2009; 50 cases of thyroidectomy was carried out. All surgical specimens 
were examined histopathologically. The cases that showed parathyroid tissue were recorded. Blood samples 
were collected for corrected serum (ionised) calcium on first postoperative day. Calcium (and vitamin D) 
treatment started from day one to all cases with low calcium levels (however clinical manifestatios of 
hypocalcimeamanifested or not). After two weeks, corrected calcium was measured. Patients with 
hypocalcaemia were followed up till 6 months postoperatively
Results: The mean age of the patients was 34.7 years and 60% were female. Thirty cases were simple 
nodular goiter while 20 cases were Graves' disease. Histopathological examination showed the presence of 
parathyroid tissue in 12 cases. Postoperative (ionised) calcium was within normal range in 45 patients while 
5 patients had low (ionised) calcium level. Clinically, two patients presented with manifestations of 
hypocalcaemia. After two weeks of calcium treatment, corrected calcium level was back to normal except in 
one case that required long term calcium (and vitamin D) treatment. That case proved to have permanent 
hypocalcaemia as calcium level was still below normal after 6 months of surgery.
Conclusions: The accidental removal of parathyroid tissue does not necessarily mean (temporary) or 
permanent hypocalcaemia. The incidence of (hypoparathyroidism in this study was lower than expected in 
relation to histopathologically proven removed parathyroid gland)(early calcium and vitamin D treatment 
decreases the morbidity of temporary and permenant hypoparathyroidism). 

DOI

10.21608/ejsur.2011.367346

Keywords

parathyroid, calcium, thyroid surgery

Authors

First Name

Tarik

Last Name

Abdel Azeez

MiddleName

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Affiliation

Department of Surgery, El-Minia University, Faculty of Medicine, Egypt

Email

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City

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Orcid

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First Name

Ahmed

Last Name

Hatem

MiddleName

-

Affiliation

Department of Surgery, El-Minia University, Faculty of Medicine, Egypt

Email

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City

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Orcid

-

First Name

Ahmed

Last Name

Kamal

MiddleName

-

Affiliation

Department of Surgery, El-Minia University, Faculty of Medicine, Egypt

Email

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Volume

30

Article Issue

4

Related Issue

49200

Issue Date

2011-10-01

Receive Date

2024-07-16

Publish Date

2011-10-01

Page Start

155

Page End

158

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_367346.html

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https://ejsur.journals.ekb.eg/service?article_code=367346

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367,346

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Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

POST-THYROIDECTOMY HYPOCALCAEMIA: CLINICAL AND HISTOPATHOLOGICAL STUDY

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Article

Created At

21 Dec 2024