Purpose: To determine the effectiveness of percutaneous transluminal angioplasty (PTA) for treatment of 
patients with the infragenicular arterial lesions as a primary choice for management of critical lower limb 
ischemia due to infragenicular arterial disease. We present the technical success, early- and medium-term
outcomes, and limb salvage rate.
Methods: The records of 57 patients undergoing infragenicular popliteal artery (IGPA) and tibial vessels PTA 
presented to vascular unit at Mansoura university hospital over a period between January 2010 and April 
2012 was reviewed. Patients underwent follow-up with clinical examinations, ABI, Duplex, and 
Arteriography. Demographic variables and cardiovascular risk factors, primary patency and limb salvage 
were analyzed.
Results: Mean follow-up was 11.08 + 3.2ranging from 3 to 13 month With Kaplan Mayer analysis, primary 
patency was 94.7%, 83.8%, and 69.3% at 3, 6, and 12 month, respectively. And limb salvage was 96.5%, 92.9%, 
and 82.4% at 3, 6, and 12 month, respectively.
Conclusions: Infragenicular angioplasty can be used as a primary intervention for CLI and it may be the only 
choice for some cases. It could be also used as a second step after correction of a proximal lesion (either by 
open surgery or endovascular) the low complication rate and relatively noninvasive nature of PTA made it 
first recommendation in infragenicular vessels.