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365059

Implementation and evaluation of axillary reverse mapping technique in breast cancer patients using patent blue dye

Article

Last updated: 29 Dec 2024

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Abstract

Introduction
. Following axillary lymph node dissection, arm lymphedema can develop in 7–77% of cases. To detect and preserve upper-limb lymphatics and lymph nodes after axillary surgery, the axillary reverse mapping (ARM) technique was developed. This procedure may help avoid arm lymphedema.
Aim of work
To establish the ARM-node involvement of cancer cells and study their location to assess the effectiveness of ARM using patent blue dye.
Methodology
At Kasr Alainy University Hospital, this prospective randomized controlled study was carried out. There were 42 breast cancer patients in total, including 21 each in the study group and the control group. Following dye injection, stained ARM lymph nodes and lymphatics were preserved in the study group during axillary lymph node (ALN) dissection if grossly negative and removed if grossly positive, whereas individuals in the control group had the standard technique. After 1 month, all subjects underwent a second evaluation, during which the arm circumference was measured and recorded at a point 10 cm near the medial epicondyle.
Results
In the study group, in 18 patients (85.7%) their lymph nodes were stained. Six patients had suspiciously colored lymph nodes that were surgically removed, but no metastatic disease was apparent in the rest of the group. Early upper-limb lymphedema was not detected in the study group (0%), with 9.5% in the control group.
Conclusion
Arm lymphedema can be avoided by doing ARM while performing ALN dissection. Future research should be conducted on more patients and for a longer length of time, according to the findings of this study.

DOI

10.4103/ejs.ejs_210_23

Keywords

breast cancer, axillary reverse mapping, Blue dye, Lymphedema

Authors

First Name

Emad

Last Name

Khallaf

MiddleName

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Affiliation

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Email

khallaf613@gmail.com

City

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Orcid

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First Name

Sherif M.

Last Name

Mokhtar

MiddleName

-

Affiliation

-

Email

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City

-

Orcid

-

First Name

Bishoy

Last Name

Mikhail

MiddleName

-

Affiliation

-

Email

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City

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Orcid

-

First Name

Mahmoud

Last Name

Ali

MiddleName

-

Affiliation

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Email

mahmoudabdelmohsen@cu.edu.eg

City

-

Orcid

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Volume

42

Article Issue

4

Related Issue

48973

Issue Date

2023-12-01

Receive Date

2023-09-18

Publish Date

2023-12-07

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_365059.html

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https://ejsur.journals.ekb.eg/service?article_code=365059

Order

365,059

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

Implementation and evaluation of axillary reverse mapping technique in breast cancer patients using patent blue dye

Details

Type

Article

Created At

21 Dec 2024