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364469

Modified technique for Kasai porto-enterostomy in biliary atresia and its impact on clinical outcome

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Last updated: 29 Dec 2024

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Abstract

Background
Traditionally, the principle of the Kasai procedure is to remove the atretic extrahepatic ducts so as to establish bile flow to the intestine at an early stage and prevent further progression of the disease. Here, we describe modifications to the procedure via a wider and deeper dissection.
Aim
To assess the new modified technique over the traditional technique used for type III biliary atresia and its impact on the clinical outcome.
Patients and methods
This is a retrospective study that assessed the outcome of 66 patients who underwent Kasai portoenterostomy (KPE) at Hepatobiliary and Pancreatic Surgery Department, National Liver Institute, Menoufia University between July 2014 and December 2017. The patients were divided into two groups and the outcome after the modified KPE were compared with the traditional KPE regarding clinical outcome and overall survival.
Results
In all, 66 patients were identified. Of these, 32 were in the traditional KPE group and 34 in the modified KPE group. The modified technique had better short-term clinical outcome than the traditional technique group at 3 and 6 month postoperatively with statistical significance (=0.006 and 0.017, respectively). The rate of native liver survival was 68.8 versus 31.5% and overall survival was 88.2 versus 65.6%.
Conclusion
Deep and long incision in fibrous remnant and meticulous anastomosis was associated with favorable outcomes.

DOI

10.4103/ejs.ejs_27_19

Keywords

biliary atresia, jaundice clearance, Kasai portoenterostomy

Authors

First Name

Ahmed

Last Name

Sallam

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Orcid

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First Name

Sherif

Last Name

Saleh

MiddleName

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Orcid

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First Name

Mohamed

Last Name

Taha

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-

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Orcid

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Volume

38

Article Issue

4

Related Issue

48956

Issue Date

2019-10-01

Receive Date

2019-02-11

Publish Date

2019-10-01

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_364469.html

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https://ejsur.journals.ekb.eg/service?article_code=364469

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364,469

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

Modified technique for Kasai porto-enterostomy in biliary atresia and its impact on clinical outcome

Details

Type

Article

Created At

21 Dec 2024