Objective: To compare laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication in terms of
postoperative acid reflux control and postoperative complications, especially dysphagia and gas bloat on a short-term
basis.
Patients and Methods: This prospective randomized study included 50 patients with gastroesophageal reflux disease
who presented at Gastrointestinal Surgical Center, Mansoura University, for antireflux surgery from August 2021 to
August 2022.
Results: The incidence of dysphagia was higher in the Nissen group than in Toupet in early postoperative follow-up
(3 months) compared with the Toupet group (P=0.008), but the incidence of dysphagia decreased among the Nissen group
during follow-up periods while no incidence of dysphagia in Toupet group (P=0.077).
Regarding heartburn score, there was no statistically significance between the two groups Toupet and Nissen (P=0.200)
at early follow-up periods. However after 18-month postoperative, Nissen group showed better control of heartburn
symptoms when compared to the Toupet group (P=0.045).
In the current study, according to quality of life after 1 year and patient satisfaction, there was no significant difference
between the two procedures (P=0.059).
Conclusion: Nissen fundoplication shows a high incidence of dysphagia and gas bloat symptoms during early postoperative
periods when compared with Toupet fundoplication, but this incidence decreases along follow-up periods. On the other
hand, Nissen fundoplication shows better acid reflux control all over the follow-up periods.