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365454

Comparative study for the outcome of living donor liver transplantation in patients with portal vein thrombosis in comparison to patients without portal vein thrombosi

Article

Last updated: 29 Dec 2024

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Abstract

Background: Portal vein thrombosis (PVT) is a relative contraindication in living donor liver transplantation (LDLT). We
monitored the outcome of adult patients with PVT in comparison to patients without PVT in LDLT..
Methods: This study is a retrospective cohort study. LDLTs that were performed at Liver Transplantation Unit in Air
Forces Hospital and Nasser Institute, between January 2016 and June 2022 were evaluated. 176 cases were divided into
two groups according to the presence of PVT, group A included 55 recipients who had PVT compared with group B
including 121 recipients without PVT..
Results: In our study (N = 176), postoperative PV complications was recorded in 11 (6.3 %) cases. Five case in each
group had postoperative PVT (9.8 % vs. 4.1 %), respectively and a single case of PV stenosis (0.8 %) was documented
in non-PVT group. All patients who develop early postoperative PV (n = 3/10) complications unfortunately died because
of it, unlike those who developed late PV complications, their 1 year survival rate was 70 % of cases and the overall
mortality rate in patients developed PV complications was 40 %.
Conclusion: PVT is established not to be a contraindication for LT but needs complex procedures and sophisticated
techniques and Surgeons should be aware of these techniques to restore adequate portal flow in transplant for recipients
with PVT.

DOI

10.21608/EJSUR.2024.274273.1008

Keywords

Liver transplantation, Living donor, portal vein thrombosis, Reconstruction, Survival, Thrombectomy

Authors

First Name

Muhammad

Last Name

Musalam

MiddleName

-

Affiliation

Department of Hepatopancreaticobiliary and Liver Transplantation, Nasser Institute for Research and Treatment, Nile Corniche, Shoubra, Cairo, Egypt

Email

musalam2007@gmail.com

City

-

Orcid

-

First Name

Amr

Last Name

Nasser

MiddleName

Abdel

Affiliation

Department of General Surgery, Hepatopancreaticobiliary Unit, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Amr

Last Name

Abdelaal

MiddleName

-

Affiliation

Department of General Surgery, Hepatopancreaticobiliary Unit, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

aaabdelaal@med.asu.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Khalil

MiddleName

-

Affiliation

Department of General Surgery, Hepatopancreaticobiliary Unit, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

abdelrazek79@hotmail.com

City

-

Orcid

-

First Name

Hatem

Last Name

Saber

MiddleName

S.

Affiliation

Department of General Surgery, Hepatopancreaticobiliary Unit, Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

43

Article Issue

3

Related Issue

48897

Issue Date

2024-07-01

Receive Date

2024-07-07

Publish Date

2024-07-01

Page Start

988

Page End

999

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_365454.html

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https://ejsur.journals.ekb.eg/service?article_code=365454

Order

365,454

Type

Original Article

Type Code

3,086

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

Comparative study for the outcome of living donor liver transplantation in patients with portal vein thrombosis in comparison to patients without portal vein thrombosi

Details

Type

Article

Created At

21 Dec 2024