Background: Securing the mesoappendix during appendectomy is a crucial step in this procedure. The current study
aimed to evaluate the perioperative outcomes of intracorporeal ligation versus Ligasure in securing the mesoappendix
during laparoscopic appendicectomy (LA).
Patients and Methods: A prospective randomized comparative study was carried out in a tertiary care hospital. Patients
who had laparoscopic appendectomy for acute appendicitis between January 2021 and January 2024 were included in
this study. Patients were allocated to one of two groups. Group I: the mesoappendix was secured by intracorporeal suture
ligation. Group L: the mesoappendix was secured by LigaSure. Demographic and perioperative data were collected,
tabulated, and analyzed by SPSS 23.
Results: A total of 100 patients underwent LA. No statistically significant difference was found between the two groups
regarding age, sex ratio, or BMI. The technique duration was 8.9±3.5 min in group I, while the duration was 4.9±2.3 min
in group L (statistically significant difference P≤0.05). None of the patients required conversion to an open surgery. The
duration of postoperative hospital stay was 12.1±2 h for group I, and 11.1±8 h for group L (P>0.05). One (2%) patient in
group I had a postoperative right iliac fossa-infected hematoma. In group L, there was no postoperative complications.
Conclusion: In LA, the incidence of perioperative complications is not affected by the method used for securing the
mesoappendix. However, intracorporeal ligation takes a longer time, which could be improved with training, it is costeffective, safe, and suitable when energy-sealing devices are not available or in low-resource facilities.