Background: Gastric ectopic pancreas is a rare developmental anomaly which is difficult to differentiate from submucosal 
tumor such as gastric stromal tumor by imaging methods. Since the treatments of the gastric ectopic pancreas and gastric 
stromal tumor are different, a correct diagnosis is essential.
Aim: To identify and investigate ectopic gastric pancreatic tissue from gastric tumors.
Patients and Methods: This prospective study was carried out from October 2021 to January 2023. During this period a 
total of 50 patients underwent a laparoscopic approach to investigate the resected tissue Histopathologically in addition to 
computed tomography (CT) imaging, all the included patients admitted to the Department of General Surgery, Al-Azhar 
University Hospitals, Al-Azhar University (Assiut Branch).
Results: Significant difference in the distribution of tumors in the gastric fundus between the two groups (P < 0.001). 
Furthermore, GPT were more likely to have the presence of peritumoral infiltration or fat-line of peritumor (P < 0.001). 
Moreover, there were significant differences in the necrosis, calcification, surface ulceration, and lymph node. Significant 
differences in CT attenuation and degree of enhancement (<0.001).
Conclusion: Histopathology and CT imaging studies differentiate between ectopic pancreatic tissues from gastric tumors. 
Ectopic pancreatic tissue is a rare pathological condition that can present as acute cholecystitis of gastric tumor.