In this work, the serum content of the trace elements; (Fe, Cu and Zn) and thyroid hormones (T3, T4 and TSH) in
hypothyroidism and hyperthyroidism patients were determined and compared to those of normal persons. The results
included the statistical values of the thyroid hormones TSH, T4, T3, iron, copper and zinc in serum patients and healthy
people between the ages of (15-60) years, as was studied by age and gender. Sixty patients and thirty normal healthy control
persons participated in this study. The results were discussed in terms of: i- Thyroid disorder; (hypothyroidism or
hyperthyroidism), ii- sex (male or female) and iii- ages (15-30, 31-45 or 46-60 years). The results of this work as discussed
indicate, the role of the trace elements in many metabolic processes either as essential nutrients or as cofactors for different
enzymes contributed directly or indirectly to the hypothyroidism. Consequently, the results suggest that the metabolism of
iron, copper and zinc is abnormal in hyperthyroidism disease.