This work deals with the establishment of a new guideline for a new disposal for low and intermediate radioactive waste in Egypt. It is only permitted in natural geological formations with acceptable seismic and tectonic parameters. The representative parameters applied for this evaluation are related to the release process of the strain energy. The examined parameters are magnitude M2, equivalent to the mean annual total strain energy release, and magnitude M3, analogous to the maximum strain energy which may be accumulated and released in a region. Empirical relation between M3 and M2 is obtained and the result shows that it has a worldwide validity. The quantity Dt, showing the time difference per year between the upper bound line (in the energy diagram) and the time since the last seismic activity (strain energy accumulation) is suggested here. An effort is made to forecast the approximate time of the next earthquake occurrence with magnitude less or equal to the maximum strain energy release. Finally, it clears that the Western Desert is a suitable region for establishing the site of radioactive waste repository.