Beta
370191

Climatotherapy at Red Sea, Hurghada, versus topical combination of corticosteroids with salicylic acid in treatment of psoriasis

Article

Last updated: 29 Dec 2024

Subjects

-

Tags

-

Abstract

Background
The comparison between the efficacy of climatotherapy and the combination of topical steroids with salicylic acid has not been done before. Climatotherapy treatment includes balneotherapy and sun exposure.
Objective
To compare the effectiveness and safeness of climate therapy at Red Sea, Hurghada, with topical corticosteroid and salicylic acid combination therapy for treating chronic plaque psoriasis.
Patients and methods
The work included 30 cases with chronic plaque psoriasis. Patients' age ranged between 9 and 60 years. Cases were classified randomly into two groups, with 15 cases each. Group I was treated with Red Sea climatotherapy (sand bath, bathing in Red Sea water, and sunlight exposure). Group II was treated with topical mix of salicylic acid (3.00%) and corticosteroids (betamethasone dipropionate 0.05%). Psoriasis area and severity index (PASI score), Skindex 16 questionnaire, and histopathological examination of skin biopsies of psoriatic lesions were performed for each patient before and after 3 weeks of treatment.
Results
A marked decrease in PASI score (P = 0.001) and of Skindex 16 (P = 0.009) and a significant difference between histopathological changes were found in cases treated with climatotherapy and in cases treated with topical combination of steroids and salicylic acid but with much more decrease in patients treated with climatotherapy. After treatment, PASI score improved by 80% in 75% of cases in group I and by 50% in 75% of patients in group II.
Conclusion
Climatotherapy is a safe, alternative treatment of psoriasis with low risk, high therapeutic effect, and no adverse effects.

DOI

10.4103/jcmrp.jcmrp_106_22

Keywords

betamethasone dipropionate, climatotherapy, Psoriasis Area and Severity Index, Psoriasis, The Red Sea, Salicylic acid

Authors

First Name

Eman

Last Name

Kamal Youssef

MiddleName

M.

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Abdel-Mageed

MiddleName

A.

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Abeer

Last Name

Mohamed

MiddleName

A.

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Mai

Last Name

Elkabsh

MiddleName

M

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Esraa

Last Name

Ahmed

MiddleName

S.E.

Affiliation

-

Email

-

City

-

Orcid

-

Volume

8

Article Issue

2

Related Issue

49494

Issue Date

2023-04-01

Publish Date

2023-04-01

Page Start

62

Page End

68

Print ISSN

2357-0121

Online ISSN

2357-013X

Link

https://jcmrp.journals.ekb.eg/article_370191.html

Detail API

https://jcmrp.journals.ekb.eg/service?article_code=370191

Order

370,191

Publication Type

Journal

Publication Title

Journal of Current Medical Research and Practice

Publication Link

https://jcmrp.journals.ekb.eg/

MainTitle

Climatotherapy at Red Sea, Hurghada, versus topical combination of corticosteroids with salicylic acid in treatment of psoriasis

Details

Type

Article

Created At

20 Dec 2024