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370123

Platelets abnormalities in children with iron deficiency anemia

Article

Last updated: 29 Dec 2024

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Abstract

Introduction
Iron deficiency is the most common nutritional deficiency in the world, responsible for ill health, lost productivity, and premature death. Iron deficiency may lead to reactive thrombocytosis and rarely thrombocytopenia.
Participants and methods
This study included 115 children with iron-deficiency anemia attending Assiut University Children Hospital, Hematology Unit, from the June 1, 2017, to the June 1, 2018. Their age ranges from 2 to 5 years. Moreover, 55 apparently healthy children with the same age group were included as a control group. All patients and controls were subjected to meticulous history taking, thorough clinical examination, hematological study, as well as stool and urine examination.
Results
The mean platelet count in our patients was significantly higher than in controls. Thrombocytopenia was noticed in one patient. Results were discussed in the light of available literatures.
Conclusion
Reactive thrombocytosis is the most frequent platelet abnormality associated with iron-deficiency anemia. The mean platelet volume, plateletcrit, platelet large cell count, and platelet large cell ratio estimate indirectly platelet activity.

DOI

10.4103/JCMRP.JCMRP_76_20

Keywords

iron, Platelet volume, thrombocytopenia, Thrombocytosis

Authors

First Name

Fahim

Last Name

Fahim

MiddleName

M.

Affiliation

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City

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Orcid

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First Name

Shabaan

Last Name

Helal

MiddleName

R.

Affiliation

-

Email

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City

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Orcid

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First Name

Eman

Last Name

Fathalla

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Andrew

Last Name

Saeed

MiddleName

N.

Affiliation

-

Email

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City

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Orcid

-

First Name

Shereen

Last Name

Galal

MiddleName

M.

Affiliation

-

Email

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City

-

Orcid

-

Volume

7

Article Issue

1

Related Issue

49488

Issue Date

2022-01-01

Publish Date

2022-01-01

Page Start

22

Page End

28

Print ISSN

2357-0121

Online ISSN

2357-013X

Link

https://jcmrp.journals.ekb.eg/article_370123.html

Detail API

https://jcmrp.journals.ekb.eg/service?article_code=370123

Order

370,123

Publication Type

Journal

Publication Title

Journal of Current Medical Research and Practice

Publication Link

https://jcmrp.journals.ekb.eg/

MainTitle

Platelets abnormalities in children with iron deficiency anemia

Details

Type

Article

Created At

20 Dec 2024