Preterm birth is delivery before 37 weeks of gestation it remains a global challenge with an incidence of 11.1% (1). Progestogens are the only medications that their use showed reduction in incidence of preterm birth (2.3) they are used in asymptomatic women who are at increased risk of preterm birth based on their history and ultrasound finding of short cervical length, their use is supported and guideline recommendation published by Society for Maternal Fetal Medicine publications committee 2012, American collage of Obstetricians and gynecology committee on practice bulletin 2012 and European Association of PerinatalMedicine.