Objective:
The aim was to determine the frequency of infection in patients with immune thrombocytopenic purpura (ITP) and to detect the effect of its eradication therapy on platelet count response in -positive patients.
Patients and methods:
stool antigen enzyme immunoassay test was done for 54 patients with ITP. -positive patients received standard triple therapy for 2 weeks. Platelet count response to eradication therapy was evaluated 2 and 3 months after the treatment.
Results:
infection was positive in 38 (70.4%) patients with ITP. Eradication of was achieved in 30 (78.9%) patients (responder group). There were statistically significant increases in platelet count (among the responder group) after eradication therapy at 2 and 3 months ( < 0.05).
Conclusion:
Eradication of infection in patients with ITP is associated with significant increase in platelet counts.