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346798

Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamics in Elderly Patients Undergoing Urologic Endoscopic Surgery

Article

Last updated: 29 Dec 2024

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Tags

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Abstract

Background:
An adjuvant of local anesthetics (LA) with spinal anesthesia (SA) increases the SA length.
Aim:
This study investigates the impact of intrathecal addition of dexamethasone to bupivacaine on improving post-spinal anesthesia hypotension (PSAH) in elderly patients.
Primary Outcomes
Amount of fluids and vasoactive drugs needed to maintain blood pressure.
Secondary Outcomes

Demographic data, including duration of anesthesia, duration of surgery, gender, age, BMI, chronic medical disease, and ASA.
Blood pressure: systolic and diastolic blood pressure and mean arterial blood pressure.
Postoperative VAS score of pain assessment.
Postoperative shivering.
Postoperative nausea and vomiting.
Post-dural puncture headache (PDPH).

Patients and Methods:
90 patients were scheduled for endoscopic bloodless urologic surgeries under SA, including cystoscopic and ureteroscopic surgeries. They were divided into 2 groups; 1st group (A) included 45 patients who received 8mg (2ml) dexamethasone in addition to 3ml bupivacaine 0.5% intrathecally, and 2nd group (B) included 45 patients who received only 3ml 0.5% bupivacaine intrathecally as a control group.
Results:
The dexamethasone group was significantly higher in mean, systolic, and diastolic blood pressure readings. The dexamethasone group received significantly lower ephedrine dose and intravenous fluids. The two groups had no significant differences in postoperative nausea and vomiting, but the postoperative pain score was significantly better.
Conclusion:
Using dexamethasone in combination with bupivacaine in patients who underwent SA would decrease the amounts of IV fluids and doses of vasopressors to maintain blood pressure. Further research is needed to confirm such findings.
 
 
 
 
 

DOI

10.21608/jcmrp.2024.346798

Keywords

dexamethasone, Spinal anesthesia, shivering, post-spinal anesthesia hypotension

Authors

First Name

Ahmed

Last Name

Mandour

MiddleName

Mohammed

Affiliation

Department of Anesthesia and Intensive Care, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

Fatma

Last Name

Abd El-Aal Ahmed

MiddleName

Ahmed

Affiliation

Department of Anesthesia and Intensive Care

Email

-

City

-

Orcid

-

First Name

Dalia

Last Name

Abbas

MiddleName

Mohamed

Affiliation

Department of Anesthesia and Intensive Care, Assiut University, Assiut, Egypt

Email

daliaelshelh@aun.edu.eg

City

-

Orcid

-

First Name

Ayman

Last Name

Mohammed Abou-Glalah

MiddleName

Abdel-Khalek

Affiliation

Department of Anesthesia and Intensive Care, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

Volume

9

Article Issue

1

Related Issue

46801

Issue Date

2024-01-01

Receive Date

2024-03-21

Publish Date

2024-01-01

Page Start

69

Page End

78

Print ISSN

2357-0121

Online ISSN

2357-013X

Link

https://jcmrp.journals.ekb.eg/article_346798.html

Detail API

https://jcmrp.journals.ekb.eg/service?article_code=346798

Order

346,798

Type

Original Article

Type Code

3,032

Publication Type

Journal

Publication Title

Journal of Current Medical Research and Practice

Publication Link

https://jcmrp.journals.ekb.eg/

MainTitle

Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamics in Elderly Patients Undergoing Urologic Endoscopic Surgery

Details

Type

Article

Created At

20 Dec 2024