The syndrome caused by coronavirus disease 2019 (COVID-19) has led to a wide spectrum of disease severity, and this has conferred immense pressures on hospitals worldwide, particularly within critical care. Given the rapid surge in clinical data from millions of people infected and the overwhelming scientific quest, we, the clinicians, need accurate evidence regarding the management of this disease. WHO has named this disease spectrum as COVID-2019. We seek to provide a comprehensive review of the fast-evolving literature including diagnosis, management, and novel therapies that are indicated in the management of COVID-19.