Fractional flow reserve (FFR) is considered the 
primary reference criterion used for the evaluation of 
functional significance of coronary artery stenosis. It 
helps the physician to define appropriate 
angiographic patients with borderline incidence 
coronary lesions that should or should not be treated 
with a stent.
FFR was first applied as part of a clinical trial in 
Egypt in 2013, and was used in clinical practice in 
2015 and was first used in our Cath Laboratory at 
Misr University for Science and Technology 
(MUST) hospital, 6 October 2016, Egypt.