Acute heart failure (AHF) is a life- threatening disease 
with a high mortality rate. The cardio-renal syndrome 
(CRS), or the relationship between the heart and the 
kidney, has gotten a lot of attention from cardiologists 
and nephrologists because of its connection to poor 
prognosis. Renal impairment is one of the most 
important predictors of outcome in both chronic heart 
disease and AHF. The Serum creatinine is used to 
assess renal dysfunction.