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VITAMIN B COMPLEX: A REVIEW of Different Types and Activities

Article

Last updated: 29 Dec 2024

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Organic, Analytical and Pharmaceutical Chemistry.

Abstract

B complex vitamins are a group of water-soluble compounds essential for numerous physiological functions in the human body. Comprising eight distinct members, including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin), these vitamins play pivotal roles in energy metabolism, DNA synthesis, and red blood cell formation. Thiamine, for instance, is crucial for converting carbohydrates into energy, while riboflavin supports tissue maintenance and growth. Niacin contributes to skin health and aids in the metabolism of fats. Pantothenic acid is essential for synthesizing fatty acids and amino acids, while pyridoxine supports neurotransmitter function. Biotin is vital for skin, hair, and nail health, and folate is integral for DNA synthesis and cell division. Cobalamin, often associated with nerve function, assists in the formation of red blood cells. These vitamins are commonly found in a variety of foods, and their deficiency can lead to various health issues, including anemia, fatigue, and neurological problems. We discuss the pharmacological activities, metabolism, and Structure-Activity Relationship (SAR), as well as the derivatives and uses of vitamins B1, B2, B3, B5 and B12.

DOI

10.21608/jpsdm.2024.257312.1009

Keywords

Thiamine, Riboflavin, Niacin, pantothenic acid, cobalamin

Authors

First Name

Akram

Last Name

H. Abdel Haleem

MiddleName

-

Affiliation

Pharmaceutical Chemistry, Faculty of Pharmacy, Misr University for science and Technology

Email

akram.hifny@must.edu.eg

City

-

Orcid

-

First Name

Manar

Last Name

Ellafy

MiddleName

Alaa

Affiliation

Pharmacy, Misr University for Science and Technology

Email

manar.ellafy@must.edu.eg

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-

Orcid

-

First Name

Norhan

Last Name

ali

MiddleName

-

Affiliation

MYST

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shimaa

Last Name

ahmed

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-

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sohaila

Last Name

sayed

MiddleName

-

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bassant

Last Name

karim

MiddleName

-

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Last Name

talaat

MiddleName

-

Affiliation

must

Email

mennata@must.edu.eg

City

-

Orcid

-

First Name

dina

Last Name

abdelbaeth omar

MiddleName

-

Affiliation

must

Email

dinaabd@must.edu.eg

City

-

Orcid

-

First Name

Dalia Mohamed

Last Name

abdel Rahman

MiddleName

-

Affiliation

must

Email

daliamo@must.edu.eg

City

-

Orcid

-

First Name

manar magdy

Last Name

Ali ismeal khedr

MiddleName

-

Affiliation

must

Email

manarmagdy@must.ed.eg

City

-

Orcid

-

First Name

Rokaya Rabiea

Last Name

Fathi Ali

MiddleName

-

Affiliation

must

Email

rokaya@must.edu.eg

City

-

Orcid

-

First Name

nourhan

Last Name

khaled

MiddleName

-

Affiliation

must

Email

nourhank@must.edu.eg

City

-

Orcid

-

First Name

reem

Last Name

mohammed

MiddleName

-

Affiliation

must

Email

reemm@must.edu.eg

City

-

Orcid

-

First Name

rana ali

Last Name

anwar ali

MiddleName

-

Affiliation

must

Email

ranaali@must.edu.eg

City

-

Orcid

-

First Name

hager

Last Name

yahia

MiddleName

-

Affiliation

must

Email

hagary@must.edu.eg

City

-

Orcid

-

First Name

eman

Last Name

abdelkawy tayel

MiddleName

-

Affiliation

must

Email

emanab@must.edu.eg

City

-

Orcid

-

First Name

marwa

Last Name

salah

MiddleName

-

Affiliation

must

Email

marwas@must.edu.eg

City

-

Orcid

-

First Name

alaa osama

Last Name

Hefzy Abd Elsatar

MiddleName

-

Affiliation

must

Email

alaaosama@must.edu.eg

City

-

Orcid

-

First Name

Mohamed Adel

Last Name

Ibrahim

MiddleName

-

Affiliation

must

Email

mohamedad@must.edu.eg

City

-

Orcid

-

First Name

Youssef abd alfattah

Last Name

youssef

MiddleName

-

Affiliation

must

Email

yossefa@must.edu.eg

City

-

Orcid

-

First Name

Osama ahmed

Last Name

abdle azim

MiddleName

-

Affiliation

must

Email

osamaah@must.edu.eg

City

-

Orcid

-

First Name

Amr taha

Last Name

shahat

MiddleName

-

Affiliation

must

Email

amrtaha@must.edu.eg

City

-

Orcid

-

First Name

Aisha Abdelazim Aly

Last Name

Abdelazim Aly

MiddleName

-

Affiliation

must

Email

aeshaab@must.edu.eg

City

-

Orcid

-

First Name

Eslam Mansour

Last Name

masoud

MiddleName

-

Affiliation

must

Email

eslamm@must.edu.eg

City

-

Orcid

-

First Name

Kareem

Last Name

samy othman

MiddleName

-

Affiliation

must

Email

kareems@must.edu.eg

City

-

Orcid

-

First Name

Aliaa

Last Name

magdy abd elmageed

MiddleName

-

Affiliation

must

Email

aliaaaa@must.edu.eg

City

-

Orcid

-

First Name

Ehab

Last Name

shehata

MiddleName

-

Affiliation

must

Email

ehabsh@must.edu.eg

City

-

Orcid

-

First Name

Hazem

Last Name

Ahmed Atalla

MiddleName

-

Affiliation

must

Email

hazem554@must.edu.eg

City

-

Orcid

-

First Name

Sohair

Last Name

Alansary

MiddleName

-

Affiliation

department of pharmaceutical chemistry, faculty of pharmacy, cairo university

Email

sohir.alansary@must.edu.eg

City

-

Orcid

-

Volume

1

Article Issue

2

Related Issue

46902

Issue Date

2024-06-01

Receive Date

2024-01-21

Publish Date

2024-06-01

Page Start

76

Page End

86

Print ISSN

3009-6553

Online ISSN

3009-6677

Article File

JPSDM_Volume 1_Issue 2_Pages 76-86.pdf

PDF . 1.7MB

Link

https://jpsdm.journals.ekb.eg/article_347759.html

Detail API

https://jpsdm.journals.ekb.eg/service?article_code=347759

Order

347,759

Type

Review Articles.

Type Code

2,974

Publication Type

Journal

Publication Title

Journal of Pharmaceutical Sciences and Drug Manufacturing-Misr University for Science and Technology

Publication Link

https://jpsdm.journals.ekb.eg/

MainTitle

VITAMIN B COMPLEX: A REVIEW of Different Types and Activities

Details

Type

Article

Created At

20 Dec 2024