338917

Age related decline of male fertility (ARDMF), the other side of the coin, a review article

Article

Last updated: 05 Jan 2025

Subjects

-

Tags

Andrology

Abstract

Background: The effect of male age on male fertility is a debatable subject. Men never stop producing sperms, but there is a decline in sperm quality as a man ages. According to the World Health Organization (WHO) starting around the age of 35, semen parameters worsen. The sperm quality parameters naturally change with age: count, motility, morphology, DNA fragmentation, and genetic mutations. Paternal age is among the factors affecting a couple's chance of conceiving and their pregnancy outcomes. Pregnancy Rate, time to conception, miscarriage risk, adverse pregnancy outcomes, and Offspring health risks are all affected by male age. Some studies have shown that paternal age does not affect pregnancy outcomes using conventional in vitro fertilization (IVF) techniques, while others report decreased pregnancy and live birth rates with increased male age.
Objective: to discuss the effect of male aging on fertility and pregnancy outcome and also on the results of assisted reproduction.
Conclusion: Male Age has a significant role in his fertility potential and would affect pregnancy prognosis as well as ART results.

DOI

10.21608/jrme.2024.265560.1009

Keywords

Aged male, male fertility, Assisted reproduction

Authors

First Name

Medhat

Last Name

Amer

MiddleName

-

Affiliation

Andrology Department, Faculty of Medicine, Cairo University, Egypt. , Adam International Hospital, Cairo, Egypt., Egyptian Foundation of Reproductive Medicine and Embryology (EFRE).

Email

medhatamer4@gmail.com

City

Giza

Orcid

-

First Name

Emad

Last Name

Fakhry

MiddleName

-

Affiliation

Adam International Hospital, Cairo, Egypt.

Email

emadfakhrylabib@gmail.com

City

-

Orcid

0000-0001-7939-5671

Volume

1

Article Issue

1

Related Issue

45864

Issue Date

2024-01-01

Receive Date

2024-01-25

Publish Date

2024-01-01

Page Start

26

Page End

31

Online ISSN

3009-7282

Link

https://jrme.journals.ekb.eg/article_338917.html

Detail API

https://jrme.journals.ekb.eg/service?article_code=338917

Order

5

Type

Mini review

Type Code

3,010

Publication Type

Journal

Publication Title

Journal of Reproductive Medicine and Embryology

Publication Link

https://jrme.journals.ekb.eg/

MainTitle

Age related decline of male fertility (ARDMF), the other side of the coin, a review article

Details

Type

Article

Created At

20 Dec 2024