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339022

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

Article

Last updated: 29 Dec 2024

Subjects

-

Tags

Pharmacognosy and Phytochemistry

Abstract

Annonaceae is a large, prominent family within the Magnoliales order, containing many genera. Among these, the genus Annona holds significance for its substantial diversity and traditional medicinal value. Annona squamosa L. is one of the most common species of this genus. This tropical species, commonly known as the sugar apple, exhibits distinct morphological features. Phytochemical investigations of A. squamosa revealed the presence of acetogenins, alkaloids, diterpenes, and cyclopeptides in various plant parts. Acetogenins, found mainly in seeds and representing the major active constituents, possess distinctive structures and biological activities. Alkaloids, predominantly isolated from leaves, represent the second major class of A. squamosa active constituents. A. squamosa exhibits a wide array of pharmacological activities encompassing anti-tumor, anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antiviral, immunomodulatory, and wound-healing properties. This comprehensive review highlights the botanical characteristics, phytochemical composition, and diverse pharmacological activities of A. squamosa and aims to be a guide for further research on A. squamosa.

DOI

10.21608/japs.2024.254019.1008

Keywords

Annonaceae, Annona squamosa, Annona, Acetogenins

Authors

First Name

Safaa

Last Name

Shokr

MiddleName

Yassin

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

Email

safaa.yassin@alexu.edu.eg

City

-

Orcid

-

First Name

Samah

Last Name

Elsohafy

MiddleName

Mostafa

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

Email

samah.elsohafy@alexu.edu.eg

City

Alexandria

Orcid

-

First Name

Fikria

Last Name

Darwish

MiddleName

Ali

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

Email

fikria_darwish@yahoo.com

City

Alexandria

Orcid

-

First Name

Masouda

Last Name

Amer

MiddleName

Elsayed

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt

Email

masouda.mohamed@alexu.edu.eg

City

Alexandria

Orcid

-

Volume

1

Article Issue

1

Related Issue

45819

Issue Date

2024-01-01

Receive Date

2023-12-08

Publish Date

2024-01-01

Page Start

82

Page End

99

Online ISSN

3009-7061

Link

https://japs.journals.ekb.eg/article_339022.html

Detail API

https://japs.journals.ekb.eg/service?article_code=339022

Order

339,022

Type

Review Article

Type Code

2,921

Publication Type

Journal

Publication Title

Journal of Advanced Pharmaceutical Sciences

Publication Link

https://japs.journals.ekb.eg/

MainTitle

Annona squamosa L.: A promising herbal remedy - Insights into its biological activities and phytochemical composition

Details

Type

Article

Created At

20 Dec 2024