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335407

Wilms’ tumor in low- and middle-income countries: survey of current practices, challenges, and priorities

Article

Last updated: 29 Dec 2024

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Abstract

Purpose
To identify the current practices and priorities in Wilms’ tumor management for surgeons in low- and middle-income countries (LMICs).
Methods
One hundred thirty-seven pediatric surgeons from 44 countries completed surveys on ’ . This survey was distributed through the Global Initiative for Children’s Surgery, Pan-African Pediatric Surgical Association, and Latin American Pediatric Surgical Oncology Group.
Results
Ninety-two respondents (67.2%) participated from 19 lower middle-income countries (43.2%). Twenty-one respondents (15.3%) participated from nine lower income countries (20.5%). Nineteen respondents (13.9%) participated from 13 upper middle-income countries (29.5%). Most providers do not obtain biopsy for suspected Wilms’ tumor (79%). Delayed resection after preoperative chemotherapy is the preferred approach (70%), which providers chose due to protocol (45%), to decrease tumor rupture (22%), and to decrease complications (8%). The providers’ goal was to prevent tumor spillage and upstaging (46%) or to prevent bleeding, complication, or other organ resections (21%). Most surgeons believed that upfront resection increased the risk of tumor spillage (72%).
Conclusion
Providers in LMICs prefer delayed resection after preoperative chemotherapy to reduce the incidence of tumor spillage and upstaging of Wilms’ tumor. An evidence-based guideline tailored to the LMIC context can be developed from these findings.

DOI

10.1186/s43159-022-00163-6

Keywords

wilms’ tumor, Nephroblastoma, Pediatrics, Oncology, Global surgery

Authors

First Name

Megan Thuy

Last Name

Vu

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Affiliation

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Email

megan.vu@bcm.edu

City

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Orcid

0000-0002-7697-7999

First Name

Jaime

Last Name

Shalkow

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Bindi

Last Name

Naik-Mathuria

MiddleName

-

Affiliation

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Email

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City

-

Orcid

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First Name

Sajid S.

Last Name

Qureshi

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Doruk

Last Name

Ozgediz

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Kokila

Last Name

Lakhoo

MiddleName

-

Affiliation

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Email

kokila.lakhoo@nds.ox.ac.uk

City

-

Orcid

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First Name

Hafeez

Last Name

Abdelhafeez

MiddleName

-

Affiliation

-

Email

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City

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Orcid

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Volume

18

Article Issue

1

Related Issue

45425

Issue Date

2022-01-01

Receive Date

2022-01-24

Publish Date

2022-05-02

Print ISSN

1687-4137

Online ISSN

2090-5394

Link

https://apsj.journals.ekb.eg/article_335407.html

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https://apsj.journals.ekb.eg/service?article_code=335407

Order

335,407

Publication Type

Journal

Publication Title

Annals of Pediatric Surgery

Publication Link

https://apsj.journals.ekb.eg/

MainTitle

Wilms’ tumor in low- and middle-income countries: survey of current practices, challenges, and priorities

Details

Type

Article

Created At

20 Dec 2024