335285

Acute fulminant necrotizing amebic colitis in a pediatric patient: a rare complication of amebiasis with high mortality—a case report

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Last updated: 05 Jan 2025

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Abstract

Background
The majority of amebic infections among humans remain asymptomatic. Rarely, the disease takes a fulminant acute course due to the development of necrotizing amebic colitis. This complication is usually found in adult patients. However, on the contrary, this case was diagnosed in a 9-year-old patient. He was transferred to the Sirimavo Bandaranayake Specialized Children’s Hospital (SBSCH), Peradeniya from the District General Hospital, Kilinochchi. To our knowledge, this is the first report of this rare complication in a child in Sri Lanka.
Case presentation
We present a case of acute fulminant necrotizing amebic colitis in a 9-year-old boy. Surgical exploration revealed extensive ulceration and multiple perforations in the entire colon. PAS-Martius Yellow 40 stain highlighted amebae with erythrophagocytosis within the necrotic debris of the ulcers. The polymerase chain reaction (PCR) that was conducted to confirm the diagnosis was positive for The post-operative course was marked with antimicrobial treatment for septicemia and the need for ventilator assistance. Antimicrobial treatment included intravenous metronidazole. The patient progressively recovered and was discharged on a normal diet.
Conclusion
This case reports an acute fulminant necrotizing amebic colitis in a 9-year-old patient. After the treatments, the patient progressively recovered and was discharged on a normal diet. infections in northern Sri Lanka should be given attention as a public health concern. Furthermore, this case highlights that acute fulminant amebic colitis requires early surgical intervention, aggressive supportive and anti-amebic treatments. Clinicians should be cognizant of this potentially fatal complication of amebic colitis.

DOI

10.1186/s43159-020-00039-7

Keywords

Acute fulminant necrotizing amebic colitis, Case Report, Child, Sri Lanka

Authors

First Name

Samantha

Last Name

Kiriwaththuduwa

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First Name

Romola

Last Name

Gnanapragasam

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First Name

Anjalie

Last Name

Amarasinghe

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First Name

Yugantha

Last Name

Adikari

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First Name

Shanika

Last Name

Ranasinghe

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First Name

Rumala

Last Name

Morel

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Email

rumala.morel@gmail.com

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0000-0001-6521-2846

First Name

Chanuka

Last Name

Dharmaratne

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First Name

Lakmalee

Last Name

Bandara

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Volume

16

Article Issue

1

Related Issue

45419

Issue Date

2020-01-01

Receive Date

2020-07-27

Publish Date

2020-09-17

Print ISSN

1687-4137

Online ISSN

2090-5394

Link

https://apsj.journals.ekb.eg/article_335285.html

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https://apsj.journals.ekb.eg/service?article_code=335285

Order

335,285

Publication Type

Journal

Publication Title

Annals of Pediatric Surgery

Publication Link

https://apsj.journals.ekb.eg/

MainTitle

Acute fulminant necrotizing amebic colitis in a pediatric patient: a rare complication of amebiasis with high mortality—a case report

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Article

Created At

20 Dec 2024