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395044

Adverse effects of chemotherapy and the interaction with anesthesia: a narrative review

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Last updated: 05 Jan 2025

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Abstract

Introduction: Many cancer patients have their main tumors surgically removed with the goal of curing them, or as part of palliative care. When a patient receives general anesthesia, the side effects of the administered chemotherapy regimens must be considered, especially those that may have significant repercussions during anesthetic care. The aim of this study is to review the existing literature to identify adverse effects of chemotherapy and known interactions between chemotherapy and anesthetic drugs, analyze the mechanisms underlying these interactions, and discuss relevant clinical implications. Methods: This integrative review searched for articles using the search terms: chemotherapy, anesthetic drugs, interaction, adverse effects and drug combination. Discussion: Negative perioperative outcomes may be related to the chemotherapy. Regarding the type of oncological surgery, factors such as blood loss, hypothermia and extended operative time influence the increase in morbimortality. Many anesthetic drugs are related to immunomodulation and moreover interact with chemotherapy, which may get better or worse cancer patients. Conclusion: It is crucial for anesthetists to have a comprehensive understanding of the potential adverse effects of chemotherapy drugs and their interactions with anesthetics.

DOI

10.21608/asja.2024.275440.1076

Keywords

Chemotherapy, adverse drug event, anesthetics agents, antineoplastic drug, cancer treatment protocol

Authors

First Name

MARINA

Last Name

DELGADO

MiddleName

AYRES

Affiliation

Av Carandaí 353 1601

Email

marina.ayres.delgado@gmail.com

City

-

Orcid

0000-0001-6428-1516

First Name

Pual

Last Name

Holzmann Neto

MiddleName

-

Affiliation

Hospital das Clinicas UFMG/Ebserh

Email

paulholzmann96@gmail.com

City

Belo Horizonte

Orcid

0000-0001-8901-4473

First Name

Andre Luis

Last Name

Drumond

MiddleName

Vieira

Affiliation

Hospital das Clinica UFMG/Ebserh

Email

avieiradrumond@gmail.com

City

Belo Horizonte

Orcid

0000-0001-5755-036X

First Name

Geovana

Last Name

de Souza

MiddleName

Torres

Affiliation

Hospital das Clinicas UFMG/Ebserh

Email

geovanatdesouza@gmail.com

City

Belo Horizonte

Orcid

0009-0004-3956-6981

First Name

Andre

Last Name

Mendonça

MiddleName

dos Santos

Affiliation

Hospital das Clinicas UFMG/Ebserh

Email

andresantosm1601@gmail.com

City

Belo Horizonte

Orcid

0000-0001-9701-3120

First Name

Camila

Last Name

Dall"Aqua

MiddleName

Gomes

Affiliation

Hospital das Clinicas UFMG/Ebserh

Email

camilag.d@hotmail.com

City

Belo Horizonte

Orcid

0000-0002-4470-4849

First Name

Bruna

Last Name

Oliveira

MiddleName

Carvalho

Affiliation

Hospital das Clínicas UFMG/Ebserh

Email

brucoliveira23@gmail.com

City

Belo Horizonte

Orcid

0000-0002-4585-4566

First Name

Bruno Vinícius

Last Name

Castello Branco

MiddleName

-

Affiliation

Hospital das Clinicas UFMG/Ebserh

Email

bruvini2004@gmail.com

City

Belo Horizonte

Orcid

0000-0003-2227-737X

First Name

David

Last Name

do Nascimento

MiddleName

Ribeiro

Affiliation

Hospital das Clínicas UFMG/Ebserh

Email

da.vi@hotmail.com

City

Belo Horizonte

Orcid

0009-0001-5017-6122

Volume

16

Article Issue

1

Related Issue

46864

Issue Date

2024-01-01

Receive Date

2024-03-07

Publish Date

2024-01-01

Print ISSN

1687-7934

Online ISSN

2090-925X

Article File

ASJA3950441704060000.pdf

PDF . 262.4kB

Link

https://asja.journals.ekb.eg/article_395044.html

Detail API

https://asja.journals.ekb.eg/service?article_code=395044

Order

395,044

Type

Review Articles

Type Code

2,882

Publication Type

Journal

Publication Title

Ain-Shams Journal of Anesthesiology

Publication Link

https://asja.journals.ekb.eg/

MainTitle

Adverse effects of chemotherapy and the interaction with anesthesia: a narrative review

Details

Type

Article

Created At

20 Dec 2024