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347488

Comparison of two different doses of hyperbaric bupivacaine with fentanyl for spinal anaesthesia in elderly patients undergoing routine endoscopic urological surgery: A randomize

Article

Last updated: 29 Dec 2024

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Tags

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Abstract

The major drawback of spinal anesthesia in elderly patients is the per operative hypotension and its sequel . We compared two doses (7.5 mg or 10 mg) of hyperbaric bupivacaine 0.5% with 25µg fentanyl in 150 elderly patients undergoing routine urological surgery with respect to hemodynamic profile .
Results: The time to onset of sensory block (min) was comparable amongst the two groups ( 2.41±0.86 and 2.25±0.79) in group A and B respectively .The mean time to regression of block to S2 level was at 3.56±0.53 hrs. in group A and 4.01±0.71 hrs in group B(p<0.0001). The maximum mean height of sensory block was at T8 level in 73.3% patients and T10 level in 18.6% patients of group A .In group B patients 58.6% had the sensory level at T6 level , in 33% patients it was at T8 and in 8% it was at T4 level .(p<0.0001). Onset of motor block was earlier in group B and was at 3.89±0.8 min over 4.23±1.01in group A. (p=0.026).The time to regression of motor block was earlier in group A ( 4.07±o.54 hrs over 4.69±0.58 hrs in group B).(p<0.0001) The decrease in MAP from baseline values was more in group B over group A (0% vs. 4.7%;p<0.05)) but the incidence of hypotension and bradycardia were statistically comparable amongst the groups .(p>0.05)
Conclusion :The use of 7.5mg bupivacaine with 25 µg fentanyl intrathecally results in adequate anaesthesia and analgesia coupled with stable hemodynamic as required for transurethral surgery of around 2 hrs.duration .

DOI

10.21608/asja.2024.250910.1020

Keywords

anaesthesia, hypotension, transurethral resection of prostate (TURP)

Authors

First Name

Neha

Last Name

Atwal

MiddleName

-

Affiliation

Anaesthetist Civil Hospital Nadaun, Himachal Pradesh, India.

Email

atwalneha92@gmail.com

City

Nadaun

Orcid

0009-0009-4880-8010

First Name

Jyoti

Last Name

Pathania

MiddleName

-

Affiliation

Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Email

pathaniajyoti7@gmail.com

City

Shimla

Orcid

0000-0002-6674-5174

First Name

Aparna

Last Name

Sharma

MiddleName

-

Affiliation

Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Email

aparnasharmaraina@gmail.com

City

Shimla

Orcid

0000-0003-0647-6088

Volume

16

Article Issue

1

Related Issue

46864

Issue Date

2024-01-01

Receive Date

2023-11-24

Publish Date

2024-01-01

Page Start

1

Page End

9

Print ISSN

1687-7934

Online ISSN

2090-925X

Link

https://asja.journals.ekb.eg/article_347488.html

Detail API

https://asja.journals.ekb.eg/service?article_code=347488

Order

347,488

Type

Original Article

Type Code

2,871

Publication Type

Journal

Publication Title

Ain-Shams Journal of Anesthesiology

Publication Link

https://asja.journals.ekb.eg/

MainTitle

Comparison of two different doses of hyperbaric bupivacaine with fentanyl for spinal anaesthesia in elderly patients undergoing routine endoscopic urological surgery: A randomized controlled study

Details

Type

Article

Created At

20 Dec 2024