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Dexamethasone as a bupivacaine adjuvant for ultrasound-guided interscalene brachial plexus block: a prospective randomized study

Article

Last updated: 29 Dec 2024

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Abstract

Background
Finding adjuvants to local anesthetic used in interscalene block that could efficiently extend the analgesia duration has recently been the focus of researchers. The aim of the work was to determine whether the addition of perineural dexamethasone to bupivacaine in-ultrasound guided interscalene block would prolong the duration of sensory analgesia in patients undergoing shoulder surgery.
Results
This prospective, randomized, double-blinded study comprised 50 patients. They were randomly subdivided into 2 groups: group C [control] and group D [dexamethasone]. We noted a significant difference regarding the timing for the first rescue analgesia being shorter in group C than in group D with a value < 0.001. Regarding postoperative analgesia, higher Ketolac consumption was noticed in group C than in group D. Patients from both groups showed excellent analgesic effects with VAS score less than 2 points up to 6 h postoperative then patients in group C had a higher VAS score compared to group D, and the difference was statistically significant ( value < 0.05). We also noticed an increase in the heart rate and mean arterial blood pressure in group C than in group D at 12 h and 24 h postoperatively.
Conclusion
We concluded that the addition of 8 mg of perineural dexamethasone to 30 ml of 0.5% bupivacaine showed improvement in the postoperative analgesia in shoulder surgery without obvious complications.

DOI

10.1186/s42077-020-00113-7

Keywords

Bupivacaine, Interscalene block, Perineural dexamethasone, Ultrasound-guided regional anesthesia

Authors

First Name

Maha Abd el Fattah Metawie

Last Name

Badran

MiddleName

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Affiliation

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Email

mahabadran@med.asu.edu.eg

City

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Orcid

0000-0003-3614-4447

First Name

Ayman Mokhtar

Last Name

Kamaly

MiddleName

-

Affiliation

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Email

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City

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Orcid

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First Name

Hadil Magdy

Last Name

Abdel Hamid

MiddleName

-

Affiliation

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Email

-

City

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Orcid

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First Name

Raham Hassan

Last Name

Mostafa

MiddleName

-

Affiliation

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Email

-

City

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Orcid

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Volume

12

Article Issue

1

Related Issue

44737

Issue Date

2020-01-01

Receive Date

2020-10-28

Publish Date

2020-11-12

Print ISSN

1687-7934

Online ISSN

2090-925X

Link

https://asja.journals.ekb.eg/article_329612.html

Detail API

https://asja.journals.ekb.eg/service?article_code=329612

Order

329,612

Publication Type

Journal

Publication Title

Ain-Shams Journal of Anesthesiology

Publication Link

https://asja.journals.ekb.eg/

MainTitle

Dexamethasone as a bupivacaine adjuvant for ultrasound-guided interscalene brachial plexus block: a prospective randomized study

Details

Type

Article

Created At

20 Dec 2024