Abstract: This study was carried out to evaluate the role of sesame seeds in helping to reduce the symptoms of osteoporosis and improving the level of calcium in the blood of women suffering from osteoporosis. A total of 30 female subjects participated in the study, which was divided into three groups of 10 people each. Group1 negative control, Group2 positive control (osteoporotic group) and Group3 women suffering osteoporosis and were given medical therapy + (200 mg/kg) per day of sesame seeds. This was for a period of three months. The results revealed that the mean values in the serum calcium of osteoporotic group (control +) decreased significantly at P<0.05, as compared to (control -) group. Serum ionized and total calcium increased in a group of women suffering from osteoporosis who were given (200 mg/kg) per day of sesame seeds for a period of three months significantly at P<0.01, as compared to control (+) group. The study found that the group treated with 200 mg/kg of sesame seeds  showed an improvement in serum calcium levels.