The abstract should not exceed 250 words and should be presented as a single paragraph,
following the style of structured abstracts. However, it should not include specific
headings. Here is the suggested structure for the abstract: (A) Background: Provide a
broad context for the research question and emphasize the study's purpose. (B) Methods:
Briefly describe the main methods or treatments used, including any relevant preregistration
numbers. Specify the species and strains of animals, if applicable. (C) Results:
Summarize the main findings of the article. (D) Conclusion: State the main conclusions or
interpretations derived from the study. It is important to ensure that the abstract is an
unbiased representation of the article. It should not include any results that are not presented
and supported in the main text, and it should not overstate the main conclusions.
Focus on highlighting novel aspects of the study and its key observations. Avoid using
non-standard or uncommon abbreviations, b There are many advances in the synthesis of
organic compounds like multi-component syntheses. Mechano-synthesis, green synthesis,
combinatorial synthesis, and bio-organic synthesis. Solvent-free Mechano synthesis is
a significant strategy for the synthesis of the target heterocyclic compounds due to its
"green chemistry" aspects; reactions are run solvent-free, atom economy with reduced
energy requirements, and easier work-up method. The concept of green chemistry has
become a tool for promoting sustainable development in laboratories and industry.