The field experiment on Globe artichoke was conducted at the Agricultural Research Center Farm (Kaha) in Egypt in two successive winter seasons (2020/2021 and 2021/2022). The present study investigated the effects of the application of vermicompost in the soil at different rates. with the combination of foliar application of microelements and Vermi-wash to varying rates on plant growth, fresh and dry weight, yield components, and chemical constituents of globe artichoke. The experiment was performed in a split-plot design; the vermicompost was added (in main plots) at different rates (1, 1.5, and 2 ton/fed.) compared to a recommended dose of compost (2 ton/fed. as a control). The subplots were foliar spraying with 1- water as a control, 2- Microelments, (Fe, Mn, Cu and Zn) at 50 g/100 liter of water and Vermi-wash10 liter/100 liter of water after 60-80-100-120 day after planting and The results showed that the interactions between (vermicompost 1.5 ton/fed and spraying vermi-wash treatments) recorded the highest total yield value Meanwhile, the combinations of (compost + vermi-wash and with microelements) recorded the lowest values of flower head yield. While the highest values for the early crop was obtained from fertilizing at a rate of 1 ton/ton vermicompost + vermin wash. Foliar spraying application of Vermi-wash and 2ton/fed. of compost increased inulin percentage. On the other hand, foliar application of micronutrients along with 1 ton/fed.of vermicompost resulted higher dry matter percentage.