This study was conducted during the 2022-2023 / 2023-2024 seasons on a private farm on the Alexandria Desert Road, to determine banana plant needs for nitrogen and potassium fertilization for three banana cultivars (Rahan, Jaffa, and Grand Naine), and to evaluate their effect on growth and yield. The analysis of the results shows a large variation in the studied measurements. The obtained results showed that the low concentrations of potassium (K2O-400 and K2O-800) had the advantage in the measurements of the length and weight of bunch and the number of hands/bunch. While the medium nitrogen treatment (N-600) was the highest in weight, length and pulp weight. We also find that most of the measurements of the control treatment recorded the lowest significant growth or yield characteristics. Also, the use of the highest concentration of nitrogen (N-900) had the lowest measures. Regarding the response of the cultivars, we find that in the measures of growth, the Rahan cultivar was the most responsive, unlike the Grand Naine cultivar, which were less significant in most measurements. On the contrary, in the yield measurements, we find that the Rahan cultivar was the lowest significant and the Jaffa cultivar was the most responsive. While the Grand Naine cultivar had the advantage in some characteristics, such as length, weight and pulp weight. Rahan cultivar was the lowest in the weight and length of the bunch. It can be confirmed that the use of different levels of nitrogen and potassium fertilizers had a significant and positive effect in the development stages.