The present research was conducted during 2022 and 2023 seasons in a private vineyard in Matay center, Minia Governorate, Egypt to enhance the vegetative growth, productivity and berry quality of Red Globe grapevines via foliar spraying with brassinolide and jasmonic acid. Fourteen-year-old vines were planted 2*3 meters apart in sandy soil with drip irrigation and trellised using the Gable system. In the last week of January, the vines were cane pruned with a bud load of 96 buds/vine. Twelve treatments were conducted as follows: three concentrations of brassinolide (0.5, 1 and 2 ppm) and two concentrations of jasmonic acid (10 and 20 ppm) were foliar sprayed either alone or together, in addition to the control treatment (foliar spraying with water). All treatments were applied three times; the 1^st time (following the bud burst stage), the 2^nd time (at fruit set stage) and the 3^rd time (two weeks following the fruit set stage). The results displayed that the combined application of brassinolide at 2 ppm plus jasmonic acid at 20 ppm attained the best results in terms of enhancing the vegetative growth traits and leaf chlorophyll content, which reflected therapy in increasing yield and improving berry physiochemical attributes of Red Globe grapevines.