Trees need to be in agreement with the surrounding environment to greatify their vital roles in urban air quality. The present study aimed to evaluate various tree species which represent the most widespread in streets of Shubra El-Kheima zone according to their tolerance to air pollution. Leaf samples of eleven tree species were collected from two sites; Shubra El-Kheima (represent polluted one) and Elqanater Elkhyeria (represent low air pollution site "as control site"). Four parameters were measured including total chlorophyll, pH, ascorbic acid and relative water content. APTI was approved to assess the plant tolerance to air pollution. Results indicated that there are differences among tree species in that parameters resulted in a variation in degree of tolerance to air pollution. Generally, Dalbergia sissoo was identified as tolerant species to air pollutants in Shubra El-Kheima zone according to APTI (14.05) followed by Ficus benjamina, Albizia lebbeck and Ficus nitida, which reached to12.04, 11.77 and 11.27, respectively and recommend to be planted as a dominant street tree. Concerning dust accumulation, tree species includes Dalbergia sissoo, Albizia lebbeck, Tipuana speciosa, Ficus nitida, Ficus benjamina, and Ficus infectoria are able to remove air dust and act as air filter which recorded 0.236, 0.222, 0.220, 0.194, 0.168 and 0.184 mg/cm2, respectively. So, they could be used for a forestation in region in which the study was conducted and the corresponding cities especially in the north and west borders where the wind blows.